C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase inhibitor, gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035268 Pkig 10090 + 2:163658386-163726158 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064703 Pkig-001 163658399-163726154 protein_coding
  ENSMUST00000099105 Pkig-003 163658415-163725688 protein_coding
  ENSMUST00000109400 Pkig-002 163694038-163726152 protein_coding
  ENSMUST00000126182 Pkig-004 163658477-163725791 protein_coding
  ENSMUST00000131228 Pkig-008 163658480-163725518 protein_coding
  ENSMUST00000135537 Pkig-006 163661499-163725473 protein_coding
  ENSMUST00000147385 Pkig-007 163658386-163723758 retained_intron
  ENSMUST00000152418 Pkig-005 163658458-163721198 protein_coding
  ENSMUST00000164399 Pkig-201 163658386-163726158 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064703ENSMUST00000099105ENSMUST00000109400ENSMUST00000135537ENSMUST00000147385ENSMUST00000164399
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064703 8.897±2.03 N/A 16.511±1.04 21.434±0.83 8.546±1.42 9.321±0.00 46.006±13.96 18.529±3.40 18.559±13.73 N/A 32.587±5.82 11.139±3.37 24.922±8.24 115.065±53.19
ENSMUST00000099105 N/A N/A N/A N/A N/A N/A N/A 15.757±0.00 16.030±3.66 N/A 13.593±0.16 N/A N/A 27.545±0.00
ENSMUST00000109400 11.932±3.45 33.629±13.13 29.475±1.53 N/A 16.853±8.70 30.597±3.57 74.014±4.13 7.844±2.29 7.357±1.65 54.162±7.87 10.146±1.54 20.874±8.71 6.546±1.64 N/A
ENSMUST00000135537 N/A N/A N/A 144.473±0.00 N/A N/A N/A N/A N/A N/A N/A 75.109±0.00 38.712±7.62 60.820±0.00
ENSMUST00000147385 1.292±0.11 N/A N/A 0.980±0.00 2.680±0.33 2.090±0.04 N/A N/A 0.732±0.00 3.529±0.20 N/A 3.108±0.82 1.941±0.00 N/A
ENSMUST00000164399 6.722±1.03 31.639±19.11 N/A 6.594±1.72 15.580±6.72 12.739±3.59 N/A 16.625±2.41 7.181±4.22 12.183±3.28 N/A 17.735±7.16 10.600±4.01 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R9 CIL_0007R9_0002 VISTA 2:163385776-163987192
CIL_0003UY CIL_0003UY_0002 CGP 2:163623272-163726158
CIL_0006IR CIL_0006IR_0003 CGP 2:163658386-163750239

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005575 ND cellular_component
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007165 IEA signal transduction
GO:0042308 IDA negative regulation of protein import into nucleus
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086471 pkig protein kinase (cAMP-dependent, catalytic) inhibitor gamma protein_coding Danio_rerio
ENSG00000168734 PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma protein_coding Homo_sapiens

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