C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methionine aminopeptidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036112 Metap2 10090 - 10:93858489-93897093 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047910 Metap2-001 93858489-93889814 protein_coding
  ENSMUST00000180375 Metap2-008 93868930-93889614 protein_coding
  ENSMUST00000180392 Metap2-013 93861581-93871649 nonsense_mediated_decay
  ENSMUST00000180688 Metap2-009 93870187-93889814 protein_coding
  ENSMUST00000180739 Metap2-005 93889689-93890294 processed_transcript
  ENSMUST00000180840 Metap2-002 93860928-93891202 protein_coding
  ENSMUST00000181009 Metap2-016 93862249-93864001 retained_intron
  ENSMUST00000181091 Metap2-007 93860929-93889775 protein_coding
  ENSMUST00000181104 Metap2-010 93879540-93889761 retained_intron
  ENSMUST00000181217 Metap2-006 93860929-93889784 protein_coding
  ENSMUST00000181236 Metap2-011 93879461-93889728 retained_intron
  ENSMUST00000181434 Metap2-004 93890041-93897093 processed_transcript
  ENSMUST00000181442 Metap2-012 93868833-93871507 retained_intron
  ENSMUST00000181470 Metap2-014 93862249-93865503 protein_coding
  ENSMUST00000181740 Metap2-003 93889928-93891129 processed_transcript
  ENSMUST00000181894 Metap2-015 93859826-93864070 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047910ENSMUST00000180392ENSMUST00000180688ENSMUST00000180840ENSMUST00000181091ENSMUST00000181217ENSMUST00000181236ENSMUST00000181442ENSMUST00000181894
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047910 1.957±0.51 N/A 2.879±0.14 3.688±0.91 1.268±0.01 N/A 1.545±0.17 1.685±0.20 8.087±7.37 1.696±0.15 9.749±0.83 4.163±0.28 N/A 2.848±0.34
ENSMUST00000180392 N/A N/A N/A 39.263±0.00 N/A N/A N/A N/A N/A N/A N/A 76.225±0.00 76.389±33.91 82.086±0.00
ENSMUST00000180688 N/A 26.908±2.79 19.038±2.25 25.683±7.60 12.117±0.46 12.397±1.08 N/A 8.084±0.00 5.307±1.51 9.438±2.88 N/A 22.986±18.15 47.814±26.91 40.764±34.29
ENSMUST00000180840 N/A N/A N/A N/A N/A N/A N/A N/A 95.168±24.30 N/A 9.638±1.90 N/A 10.363±2.87 N/A
ENSMUST00000181091 3.400±0.00 7.077±2.07 25.009±0.73 20.947±3.69 6.028±3.06 6.109±0.00 9.364±0.91 6.628±1.87 54.917±27.92 N/A 29.298±2.70 12.884±10.11 33.457±11.78 14.712±6.89
ENSMUST00000181217 10.653±2.92 N/A N/A N/A 4.652±2.36 8.201±0.53 6.190±2.20 7.454±1.38 7.960±0.59 12.161±1.42 N/A 9.203±6.64 7.009±0.00 22.203±4.13
ENSMUST00000181236 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 81.030±0.00 82.959±0.00 265.307±0.00
ENSMUST00000181442 N/A N/A N/A N/A 21.647±8.18 N/A 22.389±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000181894 N/A N/A N/A N/A 1.025±0.00 N/A N/A N/A N/A N/A N/A 1.736±0.16 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004177 ISS aminopeptidase activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005886 IEA plasma membrane
GO:0006508 IEA proteolysis
GO:0008152 IEA metabolic process
GO:0008235 ISS metalloexopeptidase activity
GO:0016485 ISS protein processing
GO:0016787 IEA hydrolase activity
GO:0018206 ISS peptidyl-methionine modification
GO:0031365 ISS N-terminal protein amino acid modification
GO:0044822 IEA poly(A) RNA binding
GO:0046872 IEA metal ion binding
GO:0070006 IEA metalloaminopeptidase activity
GO:0070084 IEA protein initiator methionine removal

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069261 metap2a methionyl aminopeptidase 2a protein_coding Danio_rerio
ENSDARG00000092768 metap2b methionyl aminopeptidase 2b protein_coding Danio_rerio
ENSG00000111142 METAP2 methionyl aminopeptidase 2 protein_coding Homo_sapiens

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