C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: euchromatic histone methyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036893 Ehmt1 10090 - 2:24790769-24919609 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046227 Ehmt1-201 24790795-24919590 protein_coding
  ENSMUST00000091348 Ehmt1-002 24791214-24919591 protein_coding
  ENSMUST00000102938 Ehmt1-001 24790769-24919609 protein_coding
  ENSMUST00000114418 Ehmt1-202 24790795-24891703 protein_coding
  ENSMUST00000114432 Ehmt1-203 24790795-24919590 protein_coding
  ENSMUST00000134775 Ehmt1-004 24791143-24806351 processed_transcript
  ENSMUST00000138805 Ehmt1-011 24806214-24825384 processed_transcript
  ENSMUST00000139000 Ehmt1-005 24835102-24919607 processed_transcript
  ENSMUST00000144672 Ehmt1-012 24806328-24807282 processed_transcript
  ENSMUST00000147147 Ehmt1-003 24791143-24884526 protein_coding
  ENSMUST00000150379 Ehmt1-006 24863893-24919598 protein_coding
  ENSMUST00000150836 Ehmt1-009 24824965-24852732 processed_transcript
  ENSMUST00000152161 Ehmt1-007 24863296-24919601 protein_coding
  ENSMUST00000152325 Ehmt1-008 24848027-24877516 protein_coding
  ENSMUST00000152636 Ehmt1-010 24806270-24839591 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046227ENSMUST00000091348ENSMUST00000102938ENSMUST00000114432ENSMUST00000134775ENSMUST00000147147ENSMUST00000152325
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046227 N/A N/A N/A N/A N/A N/A N/A N/A 1.241±0.00 N/A 0.853±0.28 N/A 2.087±0.75 N/A
ENSMUST00000091348 8.721±4.86 4.568±1.49 2.276±0.00 2.448±0.00 5.752±1.25 7.084±2.74 2.963±0.56 3.811±1.14 2.292±1.02 6.340±0.41 1.302±0.52 11.618±3.49 2.021±0.33 1.300±0.56
ENSMUST00000102938 1.626±0.00 N/A 5.258±0.31 21.874±9.41 N/A N/A 1.525±0.55 1.482±0.01 2.546±0.93 2.087±0.13 0.897±0.20 4.817±1.18 3.622±0.10 0.664±0.04
ENSMUST00000114432 N/A N/A 2.968±0.00 6.152±0.37 N/A N/A N/A N/A 1.314±0.31 N/A 1.454±0.34 6.300±2.21 2.940±1.56 0.740±0.25
ENSMUST00000134775 14.665±6.16 10.372±3.98 8.173±1.12 46.935±26.97 16.603±6.67 11.266±3.86 6.664±1.82 7.920±1.43 5.515±1.72 12.438±3.32 1.354±0.00 21.430±4.70 6.364±0.54 3.325±0.28
ENSMUST00000147147 N/A N/A N/A 4.650±0.00 3.631±0.00 N/A N/A N/A 0.864±0.00 N/A N/A N/A N/A N/A
ENSMUST00000152325 N/A N/A N/A 30.224±0.00 N/A N/A N/A N/A N/A N/A N/A 63.013±0.00 41.067±9.68 17.163±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QH CIL_0000QH_0002 CGP 2:24603887-24919609
CIL_0000QG CIL_0000QG_0003 CGP 2:24790769-24935252

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IEA p53 binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006306 IDA DNA methylation
GO:0008168 IEA methyltransferase activity
GO:0008270 IEA zinc ion binding
GO:0009790 IMP embryo development
GO:0016279 IEA protein-lysine N-methyltransferase activity
GO:0016568 IEA chromatin modification
GO:0016571 IEA histone methylation
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0018026 IMP peptidyl-lysine monomethylation
GO:0018027 IMP peptidyl-lysine dimethylation
GO:0034968 IEA histone lysine methylation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0046974 IDA histone methyltransferase activity (H3-K9 specific)
GO:0046976 IDA histone methyltransferase activity (H3-K27 specific)
GO:0051567 IDA histone H3-K9 methylation
GO:0070734 IDA histone H3-K27 methylation
GO:0070742 IPI C2H2 zinc finger domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026634 ehmt1b euchromatic histone-lysine N-methyltransferase 1b protein_coding Danio_rerio
ENSDARG00000068157 ehmt1a euchromatic histone-lysine N-methyltransferase 1a protein_coding Danio_rerio
ENSG00000181090 EHMT1 euchromatic histone-lysine N-methyltransferase 1 protein_coding Homo_sapiens

Loading