C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-inducing factor, mitochondrion-associated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036932 Aifm1 10090 - X:48474944-48513563 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037349 Aifm1-001 48474944-48513563 protein_coding
  ENSMUST00000114945 Aifm1-002 48474944-48513559 protein_coding
  ENSMUST00000124623 Aifm1-005 48485458-48486518 processed_transcript
  ENSMUST00000143466 Aifm1-003 48474944-48513426 retained_intron
  ENSMUST00000156795 Aifm1-004 48474945-48482896 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037349ENSMUST00000114945ENSMUST00000143466ENSMUST00000156795
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037349 14.594±2.45 18.612±3.24 12.188±1.80 8.736±2.62 7.614±2.02 8.194±0.67 22.672±4.69 32.956±4.03 26.850±3.81 5.803±1.37 12.973±0.87 16.071±20.45 41.467±26.28 3.460±1.58
ENSMUST00000114945 N/A N/A N/A 6.678±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000143466 N/A N/A N/A 1.289±0.14 0.777±0.00 0.697±0.00 N/A N/A N/A 0.569±0.06 N/A 1.328±0.56 N/A 0.312±0.06
ENSMUST00000156795 4.332±0.00 N/A N/A 5.498±2.66 11.037±0.00 N/A N/A N/A 8.231±0.00 N/A N/A 8.499±5.49 9.469±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SZ CIL_0000SZ_0002 CGP X:48411046-48513563
CIL_0000SY CIL_0000SY_0002 CGP X:48474944-48530232

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0004174 TAS electron-transferring-flavoprotein dehydrogenase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005743 IEA mitochondrial inner membrane
GO:0005758 ISS mitochondrial intermembrane space
GO:0005829 TAS cytosol
GO:0006915 IEA apoptotic process
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006979 TAS response to oxidative stress
GO:0008637 TAS apoptotic mitochondrial changes
GO:0010942 IMP positive regulation of cell death
GO:0016174 IDA NAD(P)H oxidase activity
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0030182 IEA neuron differentiation
GO:0032981 IEA mitochondrial respiratory chain complex I assembly
GO:0043065 TAS positive regulation of apoptotic process
GO:0045454 IEA cell redox homeostasis
GO:0046983 IEA protein dimerization activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051402 IGI neuron apoptotic process
GO:0055114 IEA oxidation-reduction process
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071949 IDA FAD binding
GO:1902510 IGI regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058088 aifm1 apoptosis-inducing factor, mitochondrion-associated 1 protein_coding Danio_rerio
ENSG00000156709 AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 protein_coding Homo_sapiens

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