C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: apoptosis-inducing factor, mitochondrion-associated 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000037349 Aifm1-001 ENSMUSG00000036932 10090 - X:48474944-48513563 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037349 14.594±2.45 18.612±3.24 12.188±1.80 8.736±2.62 7.614±2.02 8.194±0.67 22.672±4.69 32.956±4.03 26.850±3.81 5.803±1.37 12.973±0.87 16.071±20.45 41.467±26.28 3.460±1.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SZ CIL_0000SZ_0002 CGP X:48411046-48513563
CIL_0000SY CIL_0000SY_0002 CGP X:48474944-48530232

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0004174 TAS electron-transferring-flavoprotein dehydrogenase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005743 IEA mitochondrial inner membrane
GO:0005758 ISS mitochondrial intermembrane space
GO:0005829 TAS cytosol
GO:0006915 IEA apoptotic process
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006979 TAS response to oxidative stress
GO:0008637 TAS apoptotic mitochondrial changes
GO:0010942 IMP positive regulation of cell death
GO:0016174 IDA NAD(P)H oxidase activity
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0030182 IEA neuron differentiation
GO:0032981 IEA mitochondrial respiratory chain complex I assembly
GO:0043065 TAS positive regulation of apoptotic process
GO:0045454 IEA cell redox homeostasis
GO:0046983 IEA protein dimerization activity
GO:0051402 IGI neuron apoptotic process
GO:0055114 IEA oxidation-reduction process
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071949 IDA FAD binding
GO:1902510 IGI regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000287295 AIFM1-001 protein_coding Homo_sapiens 0 2582
ENST00000319908 AIFM1-002 protein_coding Homo_sapiens 0 2121
ENST00000346424 AIFM1-003 protein_coding Homo_sapiens 0 1216
ENST00000413342 AIFM1P1-001 processed_pseudogene Homo_sapiens 0 1410
ENST00000416073 AIFM1-005 nonsense_mediated_decay Homo_sapiens 0 1264
ENST00000460436 AIFM1-004 protein_coding Homo_sapiens 0 1216
ENST00000527892 AIFM1-006 nonsense_mediated_decay Homo_sapiens 0 1218
ENST00000529877 AIFM1-007 nonsense_mediated_decay Homo_sapiens 0 377
ENST00000533719 AIFM1-008 retained_intron Homo_sapiens 0 1064
ENST00000535724 AIFM1-201 protein_coding Homo_sapiens 0 1371

Loading