C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 0, group B, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037583 Nr0b2 10090 + 4:133553376-133556536 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042706 Nr0b2-001 133553376-133556536 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000042706
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000042706 0.111±0.03 89.128±20.19 0.008±0.00 0.024±0.02 0.311±0.21 0.367±0.30 11.823±4.79 2.499±0.32 46.826±48.29 0.176±0.06 4.413±2.17 0.089±0.01 0.169±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T4 CIL_0007T4_0002 VISTA 4:133429051-134030305
CIL_0001X3 CIL_0001X3_0002 CGP 4:133532542-133556536

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0009749 IEA response to glucose
GO:0019904 IEA protein domain specific binding
GO:0031100 IEA organ regeneration
GO:0032024 IEA positive regulation of insulin secretion
GO:0032403 IEA protein complex binding
GO:0042803 IEA protein homodimerization activity
GO:0042974 IEA retinoic acid receptor binding
GO:0042975 IEA peroxisome proliferator activated receptor binding
GO:0043234 IEA protein complex
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043433 ISS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046965 IEA retinoid X receptor binding
GO:0046966 IEA thyroid hormone receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044685 nr0b2a nuclear receptor subfamily 0, group B, member 2a protein_coding Danio_rerio
ENSG00000131910 NR0B2 nuclear receptor subfamily 0, group B, member 2 protein_coding Homo_sapiens

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