C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: keratinocyte differentiation factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037600 Kdf1 10090 + 4:133518963-133530790 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042919 Kdf1-001 133518992-133530790 protein_coding
  ENSMUST00000105901 Kdf1-002 133519055-133530785 protein_coding
  ENSMUST00000121797 Kdf1-005 133519083-133530787 protein_coding
  ENSMUST00000149807 Kdf1-003 133518963-133528768 protein_coding
  ENSMUST00000153811 Kdf1-004 133519023-133528491 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000042919ENSMUST00000105901ENSMUST00000121797ENSMUST00000149807ENSMUST00000153811
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000042919 0.759±0.00 0.811±0.42 0.931±0.04 0.139±0.00 0.995±0.53 6.432±1.60 N/A 6.333±1.99 0.667±0.44 1.685±0.25 0.803±0.39 5.221±3.64 0.920±0.00
ENSMUST00000105901 0.754±0.08 0.515±0.16 2.484±0.01 0.067±0.01 2.646±0.47 10.135±1.46 0.059±0.01 5.558±1.14 0.495±0.26 4.110±0.55 1.746±0.54 5.846±3.57 0.690±0.32
ENSMUST00000121797 0.022±0.00 0.362±0.08 0.410±0.00 0.043±0.01 0.405±0.07 2.840±0.71 N/A 1.727±0.18 0.218±0.13 0.956±0.08 0.463±0.17 0.937±0.23 0.295±0.00
ENSMUST00000149807 0.022±0.00 N/A N/A N/A 0.970±0.06 N/A N/A N/A N/A N/A N/A N/A 0.281±0.00
ENSMUST00000153811 N/A N/A N/A N/A N/A N/A 0.049±0.00 N/A 0.065±0.00 N/A 0.918±0.22 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T4 CIL_0007T4_0002 VISTA 4:133429051-134030305

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003334 IGI keratinocyte development
GO:0003674 ND molecular_function
GO:0005737 IDA cytoplasm
GO:0005938 IDA cell cortex
GO:0010482 IMP regulation of epidermal cell division
GO:0010839 IGI negative regulation of keratinocyte proliferation
GO:0016331 IMP morphogenesis of embryonic epithelium
GO:0030054 IDA cell junction
GO:0031252 IDA cell leading edge
GO:0045606 IMP positive regulation of epidermal cell differentiation
GO:0048589 IMP developmental growth
GO:0060887 IMP limb epidermis development
GO:0061436 IMP establishment of skin barrier
GO:2000647 IMP negative regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079834 KDF1 (1 of 2) keratinocyte differentiation factor 1 protein_coding Danio_rerio
ENSDARG00000088588 KDF1 (2 of 2) keratinocyte differentiation factor 1 protein_coding Danio_rerio
ENSG00000175707 KDF1 keratinocyte differentiation factor 1 protein_coding Homo_sapiens

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