C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: early growth response 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037868 Egr2 10090 + 10:67535475-67542188 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048289 Egr2-001 67537869-67542188 protein_coding
  ENSMUST00000105438 Egr2-002 67537870-67542188 protein_coding
  ENSMUST00000127820 Egr2-003 67538683-67542188 protein_coding
  ENSMUST00000130933 Egr2-004 67537870-67538380 protein_coding
  ENSMUST00000145754 Egr2-005 67535475-67540246 protein_coding
  ENSMUST00000145936 Egr2-006 67535583-67540381 protein_coding
  ENSMUST00000146986 Egr2-007 67537930-67539941 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048289ENSMUST00000105438ENSMUST00000127820ENSMUST00000130933ENSMUST00000145754ENSMUST00000145936
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048289 0.763±0.36 0.195±0.03 0.344±0.08 0.078±0.01 4.692±3.06 0.254±0.03 0.327±0.02 0.161±0.03 N/A 1.931±1.11 0.198±0.05 2.268±1.18 0.402±0.28 0.058±0.00
ENSMUST00000105438 0.357±0.10 0.298±0.03 N/A 0.257±0.00 2.704±0.59 0.175±0.00 0.227±0.02 N/A 0.016±0.00 N/A 0.170±0.05 0.505±0.25 N/A N/A
ENSMUST00000127820 N/A N/A 0.193±0.00 0.062±0.04 2.193±0.00 0.111±0.00 0.121±0.00 0.157±0.00 0.061±0.05 0.441±0.00 0.176±0.00 1.556±1.68 0.025±0.01 0.063±0.03
ENSMUST00000130933 N/A N/A N/A N/A N/A N/A N/A N/A 0.294±0.09 N/A N/A N/A N/A N/A
ENSMUST00000145754 N/A 0.229±0.03 N/A N/A N/A N/A 0.256±0.00 N/A 0.085±0.00 N/A 0.333±0.00 N/A N/A 0.081±0.01
ENSMUST00000145936 N/A 0.271±0.15 N/A 0.201±0.00 5.488±1.24 0.209±0.07 0.364±0.04 0.333±0.04 0.182±0.00 N/A N/A 3.117±1.35 N/A 0.248±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006611 IDA protein export from nucleus
GO:0007611 IEA learning or memory
GO:0007622 IDA rhythmic behavior
GO:0008045 IGI motor neuron axon guidance
GO:0014037 IMP Schwann cell differentiation
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0021569 IGI rhombomere 3 development
GO:0021612 IGI facial nerve structural organization
GO:0021660 IMP rhombomere 3 formation
GO:0021666 IMP rhombomere 5 formation
GO:0030278 IMP regulation of ossification
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032868 IEA response to insulin
GO:0035284 IMP brain segmentation
GO:0035914 IMP skeletal muscle cell differentiation
GO:0042552 IMP myelination
GO:0043066 IBA negative regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045444 IMP fat cell differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048168 IBA regulation of neuronal synaptic plasticity
GO:0071310 IDA cellular response to organic substance
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044098 egr2a early growth response 2a protein_coding Danio_rerio
ENSG00000122877 EGR2 early growth response 2 protein_coding Homo_sapiens

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