C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 2A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038456 Dennd2a 10090 - 6:39462378-39557867 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036877 Dennd2a-001 39462378-39557867 protein_coding
  ENSMUST00000145541 Dennd2a-004 39468204-39470324 retained_intron
  ENSMUST00000149162 Dennd2a-003 39463253-39489166 retained_intron
  ENSMUST00000154149 Dennd2a-002 39497137-39557867 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036877ENSMUST00000149162ENSMUST00000154149
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036877 5.172±1.68 0.261±0.06 4.538±0.50 6.702±2.63 2.510±0.49 0.835±0.34 1.061±0.34 1.286±0.27 0.541±0.27 4.495±0.46 0.570±0.23 5.586±2.41 5.366±1.45 0.464±0.10
ENSMUST00000149162 5.229±2.06 2.355±0.67 N/A 4.374±0.00 6.478±2.54 2.372±0.60 1.135±0.34 1.591±0.46 0.502±0.06 7.365±1.39 N/A 10.698±2.30 4.366±0.02 2.870±1.54
ENSMUST00000154149 N/A N/A N/A N/A N/A 0.649±0.00 N/A 0.472±0.00 0.284±0.08 N/A N/A 3.124±0.86 8.429±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZU CIL_0008ZU_0002 VISTA 6:38939568-39543498
CIL_000306 CIL_000306_0002 CGP 6:39462378-39596595

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0015031 IEA protein transport
GO:0015629 ISS actin cytoskeleton
GO:0017112 ISS Rab guanyl-nucleotide exchange factor activity
GO:0032851 ISS positive regulation of Rab GTPase activity
GO:0042147 ISS retrograde transport, endosome to Golgi

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000146966 DENND2A DENN/MADD domain containing 2A protein_coding Homo_sapiens

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