C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: STIP1 homology and U-Box containing protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039615 Stub1 10090 - 17:25830636-25833361 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044911 Stub1-201 25830636-25833361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044911
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044911 70.608±3.51 98.779±8.56 99.898±3.27 101.677±32.53 45.397±14.48 67.058±5.73 60.611±4.51 60.908±0.78 49.928±17.91 57.881±4.29 36.910±5.94 70.911±12.40 63.189±27.07 31.157±11.36

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 ISS ubiquitin ligase complex
GO:0000209 ISS protein polyubiquitination
GO:0001664 IEA G-protein coupled receptor binding
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006281 IEA DNA repair
GO:0006457 TAS protein folding
GO:0006511 ISS ubiquitin-dependent protein catabolic process
GO:0006515 IMP misfolded or incompletely synthesized protein catabolic process
GO:0016567 TAS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0019899 IEA enzyme binding
GO:0019900 IEA kinase binding
GO:0030544 ISS Hsp70 protein binding
GO:0030579 ISS ubiquitin-dependent SMAD protein catabolic process
GO:0030674 TAS protein binding, bridging
GO:0030911 ISS TPR domain binding
GO:0030968 IDA endoplasmic reticulum unfolded protein response
GO:0031072 TAS heat shock protein binding
GO:0031371 TAS ubiquitin conjugating enzyme complex
GO:0031398 ISS positive regulation of protein ubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031943 ISS regulation of glucocorticoid metabolic process
GO:0032091 IDA negative regulation of protein binding
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0042405 IEA nuclear inclusion body
GO:0042803 IDA protein homodimerization activity
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045111 IEA intermediate filament cytoskeleton
GO:0046332 ISS SMAD binding
GO:0051443 IDA positive regulation of ubiquitin-protein transferase activity
GO:0051604 TAS protein maturation
GO:0051787 IEA misfolded protein binding
GO:0051865 ISS protein autoubiquitination
GO:0051879 ISS Hsp90 protein binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070534 ISS protein K63-linked ubiquitination
GO:0071218 IMP cellular response to misfolded protein
GO:0090035 IEA positive regulation of chaperone-mediated protein complex assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045228 stub1 STIP1 homology and U-Box containing protein 1 protein_coding Danio_rerio
ENSG00000103266 STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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