Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	leucine aminopeptidase 3
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000039682	Lap3	10090	+	5:45493374-45512674	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000046122		Lap3-001	45493374-45512674	protein_coding
	ENSMUST00000131289		Lap3-003	45500339-45504800	retained_intron
	ENSMUST00000135413		Lap3-002	45498230-45504829	retained_intron
	ENSMUST00000137699		Lap3-004	45493504-45500736	retained_intron
	ENSMUST00000146811		Lap3-005	45509209-45511373	retained_intron

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000046122	9.174±2.35	3.458±2.43	12.833±3.35	5.608±0.93	5.839±2.36	5.471±2.76	7.643±1.60	36.933±8.39	35.688±18.29	6.145±2.41	12.073±2.66	12.604±6.42	23.520±16.40	4.304±1.61
ENSMUST00000137699	N/A	N/A	N/A	16.392±0.00	N/A	N/A	N/A	N/A	N/A	N/A	5.891±0.00	52.116±0.00	13.837±0.00	21.222±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_00026N	CIL_00026N_0002	CGP	5:45453751-45512674
CIL_0005X6	CIL_0005X6_0002	CGP	5:45493374-45529276

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004177	IEA	aminopeptidase activity
GO:0005634	IEA	nucleus
GO:0005737	IEA	cytoplasm
GO:0005739	IDA	mitochondrion
GO:0005802	ISO	trans-Golgi network
GO:0005925	IEA	focal adhesion
GO:0006508	IEA	proteolysis
GO:0008233	IDA	peptidase activity
GO:0008235	IEA	metalloexopeptidase activity
GO:0030145	IEA	manganese ion binding
GO:0070062	IEA	extracellular vesicular exosome

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000061981	lap3	leucine aminopeptidase 3	protein_coding	Danio_rerio
ENSG00000002549	LAP3	leucine aminopeptidase 3	protein_coding	Homo_sapiens

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