C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039910 Cited2 10090 + 10:17723228-17725673 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038107 Cited2-201 17723228-17725673 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038107
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038107 12.068±2.21 39.842±8.45 10.597±0.49 27.759±16.30 18.066±8.01 45.986±6.12 9.398±1.87 32.867±2.61 15.228±3.48 30.919±5.99 16.915±5.69 62.530±18.70 167.090±76.22 6.730±2.99

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0001106 IEA RNA polymerase II transcription corepressor activity
GO:0001568 IMP blood vessel development
GO:0001570 IMP vasculogenesis
GO:0001666 ISS response to hypoxia
GO:0001701 IMP in utero embryonic development
GO:0001829 IMP trophectodermal cell differentiation
GO:0001841 IMP neural tube formation
GO:0001843 IMP neural tube closure
GO:0001889 IMP liver development
GO:0001892 IMP embryonic placenta development
GO:0001944 IGI vasculature development
GO:0001947 IMP heart looping
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0002521 IMP leukocyte differentiation
GO:0003151 IMP outflow tract morphogenesis
GO:0003156 IMP regulation of organ formation
GO:0003197 IMP endocardial cushion development
GO:0003281 IMP ventricular septum development
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003712 TAS transcription cofactor activity
GO:0003713 ISS transcription coactivator activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007368 IMP determination of left/right symmetry
GO:0007417 IMP central nervous system development
GO:0007422 IMP peripheral nervous system development
GO:0007507 IMP heart development
GO:0007530 IMP sex determination
GO:0007569 IEA cell aging
GO:0008283 ISS cell proliferation
GO:0008584 IGI male gonad development
GO:0009612 IEA response to mechanical stimulus
GO:0010628 ISS positive regulation of gene expression
GO:0010629 ISS negative regulation of gene expression
GO:0021602 IMP cranial nerve morphogenesis
GO:0022409 IMP positive regulation of cell-cell adhesion
GO:0030325 IMP adrenal gland development
GO:0030336 IEA negative regulation of cell migration
GO:0030511 IDA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030851 IMP granulocyte differentiation
GO:0034405 IEA response to fluid shear stress
GO:0035035 IEA histone acetyltransferase binding
GO:0035360 ISS positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0035802 IMP adrenal cortex formation
GO:0035914 IMP skeletal muscle cell differentiation
GO:0043066 IMP negative regulation of apoptotic process
GO:0043627 ISS response to estrogen
GO:0045787 IMP positive regulation of cell cycle
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI SMAD binding
GO:0046697 IMP decidualization
GO:0048536 IMP spleen development
GO:0048538 IGI thymus development
GO:0048596 IGI embryonic camera-type eye morphogenesis
GO:0048821 IMP erythrocyte development
GO:0050693 IEA LBD domain binding
GO:0060136 IMP embryonic process involved in female pregnancy
GO:0060349 IMP bone morphogenesis
GO:0060411 IMP cardiac septum morphogenesis
GO:0060412 IMP ventricular septum morphogenesis
GO:0060971 IMP embryonic heart tube left/right pattern formation
GO:0061156 IMP pulmonary artery morphogenesis
GO:0061308 IMP cardiac neural crest cell development involved in heart development
GO:0061371 IMP determination of heart left/right asymmetry
GO:0061428 IEA negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070986 IMP left/right axis specification
GO:0071363 IEA cellular response to growth factor stimulus
GO:1900164 IMP nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
GO:2000020 IMP positive regulation of male gonad development
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030905 cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 protein_coding Danio_rerio
ENSG00000164442 CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 protein_coding Homo_sapiens

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