C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164442 CITED2 9606 - 6:139371807-139374620 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367651 CITED2-001 139371807-139374620 protein_coding
  ENST00000536159 CITED2-201 139372255-139374362 protein_coding
  ENST00000537332 CITED2-202 139372255-139374213 protein_coding
  ENST00000618718 CITED2-203 139373074-139374605 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367651ENST00000537332ENST00000618718
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367651 N/A 1.550±0.00 5.869±0.00 1.194±0.65 5.016±1.28 4.683±0.00 1.021±0.00 4.984±0.00 2.892±0.00 17.684±0.00 N/A 6.104±3.72 N/A N/A
ENST00000537332 N/A N/A N/A 3.530±0.00 3.520±0.00 5.006±0.00 7.323±4.31 5.174±0.00 1.773±0.00 15.516±0.00 20.593±16.87 24.902±20.68 94.380±48.11 9.161±5.42
ENST00000618718 67.769±0.00 16.405±0.00 2.979±0.00 5.072±1.26 53.924±0.00 47.840±0.00 13.437±9.20 12.303±4.65 N/A 41.190±0.00 N/A 43.068±20.33 104.555±45.21 11.702±2.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00030P CIL_00030P_0002 CGP 6:139240061-139374620
CIL_00030Q CIL_00030Q_0002 CGP 6:139371807-142088799

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 ISS nuclear chromatin
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001105 IEA RNA polymerase II transcription coactivator activity
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0001568 IEA blood vessel development
GO:0001570 IEA vasculogenesis
GO:0001666 IMP response to hypoxia
GO:0001701 IEA in utero embryonic development
GO:0001829 IEA trophectodermal cell differentiation
GO:0001841 IEA neural tube formation
GO:0001843 IEA neural tube closure
GO:0001889 ISS liver development
GO:0001892 IEA embryonic placenta development
GO:0001944 IEA vasculature development
GO:0001947 IEA heart looping
GO:0002089 IEA lens morphogenesis in camera-type eye
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0002521 IEA leukocyte differentiation
GO:0003151 ISS outflow tract morphogenesis
GO:0003156 ISS regulation of organ formation
GO:0003197 IEA endocardial cushion development
GO:0003281 IEA ventricular septum development
GO:0003682 ISS chromatin binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IMP:IEA nucleus
GO:0005737 IMP cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007368 ISS determination of left/right symmetry
GO:0007417 IEA central nervous system development
GO:0007422 IEA peripheral nervous system development
GO:0007507 ISS heart development
GO:0007530 ISS sex determination
GO:0007569 IEA cell aging
GO:0008283 IDA cell proliferation
GO:0008584 IEA male gonad development
GO:0009612 IEA response to mechanical stimulus
GO:0010628 IDA positive regulation of gene expression
GO:0010629 IDA negative regulation of gene expression
GO:0021602 IEA cranial nerve morphogenesis
GO:0022409 ISS positive regulation of cell-cell adhesion
GO:0030325 IEA adrenal gland development
GO:0030336 IMP negative regulation of cell migration
GO:0030511 ISS positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030851 IEA granulocyte differentiation
GO:0034405 IMP response to fluid shear stress
GO:0035035 IDA histone acetyltransferase binding
GO:0035360 IDA positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0035802 ISS adrenal cortex formation
GO:0035914 IEA skeletal muscle cell differentiation
GO:0043066 ISS negative regulation of apoptotic process
GO:0043627 IDA response to estrogen
GO:0045787 ISS positive regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IEA SMAD binding
GO:0046697 IEA decidualization
GO:0048536 ISS spleen development
GO:0048538 IEA thymus development
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048821 IEA erythrocyte development
GO:0050693 IPI LBD domain binding
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0060349 IEA bone morphogenesis
GO:0060411 IEA cardiac septum morphogenesis
GO:0060412 ISS ventricular septum morphogenesis
GO:0060971 ISS embryonic heart tube left/right pattern formation
GO:0061156 IEA pulmonary artery morphogenesis
GO:0061308 IEA cardiac neural crest cell development involved in heart development
GO:0061371 IEA determination of heart left/right asymmetry
GO:0061428 IDA negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070986 ISS left/right axis specification
GO:0071363 IEA cellular response to growth factor stimulus
GO:1900164 ISS nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
GO:2000020 ISS positive regulation of male gonad development
GO:2001141 IDA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030905 cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 protein_coding Danio_rerio
ENSMUSG00000039910 Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 protein_coding Mus_musculus

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