C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diacylglycerol kinase zeta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040479 Dgkz 10090 - 2:91932824-91975864 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028667 Dgkz-002 91932826-91963657 protein_coding
  ENSMUST00000099709 Dgkz-001 91932824-91975864 protein_coding
  ENSMUST00000111303 Dgkz-003 91932827-91950427 protein_coding
  ENSMUST00000124427 Dgkz-007 91935907-91938028 processed_transcript
  ENSMUST00000126473 Dgkz-006 91941009-91945257 processed_transcript
  ENSMUST00000128152 Dgkz-004 91932824-91965587 nonsense_mediated_decay
  ENSMUST00000128902 Dgkz-009 91933442-91935499 retained_intron
  ENSMUST00000130023 Dgkz-008 91933781-91935600 retained_intron
  ENSMUST00000134103 Dgkz-012 91933236-91933932 retained_intron
  ENSMUST00000138894 Dgkz-010 91933384-91934581 retained_intron
  ENSMUST00000142090 Dgkz-005 91940758-91950311 nonsense_mediated_decay
  ENSMUST00000142231 Dgkz-013 91932827-91965600 nonsense_mediated_decay
  ENSMUST00000148297 Dgkz-011 91933455-91934511 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028667ENSMUST00000099709ENSMUST00000111303ENSMUST00000128152ENSMUST00000142231ENSMUST00000148297
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028667 16.231±6.27 9.945±1.98 N/A 30.669±23.36 26.793±4.12 52.024±5.26 6.815±1.19 29.629±5.82 8.711±2.13 24.011±3.01 13.386±2.53 22.506±5.41 8.124±4.36 3.376±0.68
ENSMUST00000099709 N/A N/A N/A 5.179±0.81 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000111303 9.533±3.32 7.603±1.96 24.961±0.69 N/A 18.178±2.40 13.966±0.90 8.660±2.56 N/A 12.736±4.80 13.002±1.37 7.433±2.64 16.227±3.33 4.351±0.00 1.096±0.00
ENSMUST00000128152 N/A 6.111±0.84 N/A N/A 11.981±0.04 N/A N/A N/A 2.300±0.61 19.985±0.10 N/A 11.453±0.00 N/A N/A
ENSMUST00000142231 9.467±1.08 N/A N/A 73.583±0.00 N/A N/A 6.181±0.00 8.130±0.00 4.974±2.63 N/A N/A 13.243±3.65 9.039±1.78 N/A
ENSMUST00000148297 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.450±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001727 IEA lipid kinase activity
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0004857 IDA enzyme inhibitor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008022 IEA protein C-terminus binding
GO:0016310 IEA phosphorylation
GO:0030027 IEA lamellipodium
GO:0031571 IEA mitotic G1 DNA damage checkpoint
GO:0035556 IEA intracellular signal transduction
GO:0043086 IDA negative regulation of catalytic activity
GO:0045930 IEA negative regulation of mitotic cell cycle
GO:0046580 IMP negative regulation of Ras protein signal transduction
GO:0046834 IEA lipid phosphorylation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014439 dgkza diacylglycerol kinase, zeta a protein_coding Danio_rerio
ENSDARG00000076025 dgkzb diacylglycerol kinase, zeta b protein_coding Danio_rerio
ENSG00000149091 DGKZ diacylglycerol kinase, zeta protein_coding Homo_sapiens

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