C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diacylglycerol kinase, zeta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149091 DGKZ 9606 + 11:46332905-46380554 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318201 DGKZ-024 46347588-46380367 protein_coding
  ENST00000343674 DGKZ-001 46332905-46380554 protein_coding
  ENST00000421244 DGKZ-023 46347588-46379947 protein_coding
  ENST00000454345 DGKZ-002 46361595-46380554 protein_coding
  ENST00000456247 DGKZ-022 46347572-46380554 protein_coding
  ENST00000524448 DGKZ-013 46367652-46371384 protein_coding
  ENST00000524869 DGKZ-018 46374429-46375868 protein_coding
  ENST00000524984 DGKZ-007 46345437-46380554 nonsense_mediated_decay
  ENST00000525242 DGKZ-012 46338598-46368045 protein_coding
  ENST00000525434 DGKZ-014 46361522-46367656 processed_transcript
  ENST00000527211 DGKZ-010 46376520-46380551 retained_intron
  ENST00000527674 DGKZ-006 46345434-46369175 retained_intron
  ENST00000527903 DGKZ-017 46371725-46372897 retained_intron
  ENST00000527911 DGKZ-008 46347463-46380282 protein_coding
  ENST00000528173 DGKZ-009 46367315-46380553 retained_intron
  ENST00000528615 DGKZ-003 46345403-46380110 protein_coding
  ENST00000529660 DGKZ-020 46377148-46379568 processed_transcript
  ENST00000529698 DGKZ-021 46375024-46377350 retained_intron
  ENST00000531879 DGKZ-004 46345432-46379080 retained_intron
  ENST00000532868 DGKZ-005 46345267-46380120 protein_coding
  ENST00000532941 DGKZ-019 46377970-46378927 retained_intron
  ENST00000533376 DGKZ-016 46347523-46371384 nonsense_mediated_decay
  ENST00000534215 DGKZ-015 46361607-46368007 processed_transcript
  ENST00000534802 DGKZ-011 46377968-46380551 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318201ENST00000421244ENST00000454345ENST00000456247ENST00000524869ENST00000524984ENST00000527211ENST00000527911ENST00000528173ENST00000528615ENST00000529698ENST00000532868
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318201 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.796±0.00 5.943±0.00 N/A
ENST00000421244 N/A N/A 1.577±0.00 17.700±0.00 3.646±0.00 N/A 0.605±0.00 0.610±0.00 0.848±0.00 N/A 3.664±1.06 0.735±0.00 N/A N/A
ENST00000454345 N/A N/A N/A N/A N/A N/A 2.027±1.80 N/A N/A N/A N/A N/A N/A 3.729±0.00
ENST00000456247 N/A N/A N/A 11.301±0.80 N/A N/A 0.322±0.00 3.012±0.00 0.703±0.00 0.746±0.00 N/A 6.773±1.12 11.251±1.53 4.444±0.00
ENST00000524869 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 32.691±0.00 N/A N/A
ENST00000524984 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.780±0.00 N/A
ENST00000527211 N/A N/A N/A N/A N/A N/A N/A 0.081±0.00 N/A N/A N/A 2.000±0.00 N/A 2.160±0.00
ENST00000527911 2.133±0.00 N/A N/A 16.111±0.00 N/A 1.123±0.00 N/A 2.399±0.00 N/A N/A 5.107±0.00 14.950±0.00 13.139±7.96 12.018±0.00
ENST00000528173 N/A 3.403±0.00 N/A N/A 0.541±0.00 N/A N/A 0.929±0.00 N/A 1.460±0.00 N/A N/A N/A N/A
ENST00000528615 2.655±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000529698 N/A N/A N/A N/A N/A N/A N/A N/A 1.812±0.00 N/A N/A N/A N/A N/A
ENST00000532868 N/A N/A N/A N/A N/A N/A 0.163±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UT CIL_0002UT_0002 CGP 11:46277661-46380554
CIL_0002US CIL_0002US_0003 CGP 11:46332905-46383837

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001727 IDA lipid kinase activity
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0004857 IEA enzyme inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0008022 IDA protein C-terminus binding
GO:0016310 IEA phosphorylation
GO:0016477 NAS cell migration
GO:0030027 IDA lamellipodium
GO:0030168 TAS platelet activation
GO:0031571 IGI mitotic G1 DNA damage checkpoint
GO:0035556 IEA intracellular signal transduction
GO:0043086 IEA negative regulation of catalytic activity
GO:0045930 IGI negative regulation of mitotic cell cycle
GO:0046580 IEA negative regulation of Ras protein signal transduction
GO:0046834 IDA lipid phosphorylation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014439 dgkza diacylglycerol kinase, zeta a protein_coding Danio_rerio
ENSDARG00000076025 dgkzb diacylglycerol kinase, zeta b protein_coding Danio_rerio
ENSMUSG00000040479 Dgkz diacylglycerol kinase zeta protein_coding Mus_musculus

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