C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tet methylcytosine dioxygenase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040943 Tet2 10090 - 3:133463679-133544390 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000098603 Tet2-201 133463679-133544390 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000098603
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000098603 2.566±0.42 5.185±0.70 2.892±0.29 2.720±0.64 2.686±1.32 2.489±0.74 1.755±0.34 2.097±1.04 1.180±0.57 3.602±0.79 1.108±0.40 3.040±1.43 0.837±0.44 0.213±0.01

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002318 IMP myeloid progenitor cell differentiation
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IC nucleus
GO:0006211 ISS 5-methylcytosine catabolic process
GO:0006493 IMP protein O-linked glycosylation
GO:0007049 IEA cell cycle
GO:0008198 ISS ferrous iron binding
GO:0008270 ISS zinc ion binding
GO:0009791 IMP post-embryonic development
GO:0019857 IMP 5-methylcytosine metabolic process
GO:0019858 IMP cytosine metabolic process
GO:0020027 IMP hemoglobin metabolic process
GO:0030097 IMP hemopoiesis
GO:0030099 IMP myeloid cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IMP spleen development
GO:0048872 IMP homeostasis of number of cells
GO:0055114 IEA oxidation-reduction process
GO:0061484 IMP hematopoietic stem cell homeostasis
GO:0070579 IDA methylcytosine dioxygenase activity
GO:0072576 IMP liver morphogenesis
GO:0080111 IDA DNA demethylation
GO:0080182 IMP histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076928 tet2 tet methylcytosine dioxygenase 2 protein_coding Danio_rerio
ENSG00000168769 TET2 tet methylcytosine dioxygenase 2 protein_coding Homo_sapiens

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