C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled homolog 7 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041075 Fzd7 10090 + 1:59482424-59486955 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000114246 Fzd7-001 59482424-59486955 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114246
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114246 9.579±5.81 7.675±1.77 17.379±0.05 2.175±0.90 13.453±4.71 9.270±0.77 2.427±0.42 4.290±1.03 3.478±1.92 20.606±1.34 11.448±3.79 13.440±4.86 3.279±2.03 0.686±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CR CIL_0009CR_0002 VISTA 1:59040862-59642046
CIL_0000JM CIL_0000JM_0003 CGP 1:59256906-59486955
CIL_00020N CIL_00020N_0002 CGP 1:59482424-59636417

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0004930 IEA G-protein coupled receptor activity
GO:0005109 IEA frizzled binding
GO:0005515 IPI protein binding
GO:0005737 IBA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007223 IBA Wnt signaling pathway, calcium modulating pathway
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008406 IBA gonad development
GO:0010812 IMP negative regulation of cell-substrate adhesion
GO:0014834 IMP skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0016021 IEA integral component of membrane
GO:0017147 IPI Wnt-protein binding
GO:0019827 IEA stem cell maintenance
GO:0030165 IBA PDZ domain binding
GO:0030855 IBA epithelial cell differentiation
GO:0032589 IBA neuron projection membrane
GO:0033077 IMP T cell differentiation in thymus
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0035412 IEA regulation of catenin import into nucleus
GO:0035567 IGI non-canonical Wnt signaling pathway
GO:0038031 IEA non-canonical Wnt signaling pathway via JNK cascade
GO:0042327 IEA positive regulation of phosphorylation
GO:0042666 IEA negative regulation of ectodermal cell fate specification
GO:0042813 IMP Wnt-activated receptor activity
GO:0045177 IBA apical part of cell
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048103 IMP somatic stem cell division
GO:0060054 IEA positive regulation of epithelial cell proliferation involved in wound healing
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060231 IEA mesenchymal to epithelial transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027589 fzd7b frizzled homolog 7b protein_coding Danio_rerio
ENSDARG00000060004 fzd7a frizzled homolog 7a protein_coding Danio_rerio
ENSG00000155760 FZD7 frizzled class receptor 7 protein_coding Homo_sapiens

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