C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: engulfment and cell motility 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041112 Elmo1 10090 + 13:20090596-20606528 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072519 Elmo1-001 20090619-20606528 protein_coding
  ENSMUST00000180626 Elmo1-003 20111512-20342888 retained_intron
  ENSMUST00000180767 Elmo1-004 20472726-20592444 retained_intron
  ENSMUST00000181429 Elmo1-002 20090596-20264007 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072519ENSMUST00000181429
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072519 10.475±0.73 13.958±3.51 7.473±0.34 16.041±5.11 13.133±4.93 8.959±3.28 3.927±0.32 2.657±0.30 2.727±1.82 20.953±4.36 0.889±0.33 21.283±8.04 7.479±1.77 11.772±4.94
ENSMUST00000181429 N/A 15.265±0.00 N/A N/A N/A 6.590±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 ISS plasma membrane
GO:0006909 IDA phagocytosis
GO:0006911 ISS phagocytosis, engulfment
GO:0006915 IEA apoptotic process
GO:0006928 ISS cellular component movement
GO:0016020 IEA membrane
GO:0016601 ISS Rac protein signal transduction
GO:0017124 IEA SH3 domain binding
GO:0030029 IDA actin filament-based process
GO:0030036 ISS actin cytoskeleton organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019258 elmo1 engulfment and cell motility 1 (ced-12 homolog, C. elegans) protein_coding Danio_rerio
ENSDARG00000055400 ELMO1 (2 of 2) engulfment and cell motility 1 protein_coding Danio_rerio
ENSG00000155849 ELMO1 engulfment and cell motility 1 protein_coding Homo_sapiens

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