C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: engulfment and cell motility 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155849 ELMO1 9606 - 7:36854361-37449249 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310758 ELMO1-001 36854361-37449249 protein_coding
  ENST00000396040 ELMO1-019 36854462-36985060 protein_coding
  ENST00000396045 ELMO1-002 36854361-36986509 protein_coding
  ENST00000420636 ELMO1-015 36894854-37216689 nonsense_mediated_decay
  ENST00000424212 ELMO1-014 37211085-37216698 protein_coding
  ENST00000433246 ELMO1-013 37096678-37222688 protein_coding
  ENST00000442504 ELMO1-008 36855291-37353668 protein_coding
  ENST00000445322 ELMO1-005 37314865-37449186 protein_coding
  ENST00000448602 ELMO1-003 36855551-37449223 protein_coding
  ENST00000453399 ELMO1-006 37271832-37448950 protein_coding
  ENST00000455119 ELMO1-012 37233105-37342763 protein_coding
  ENST00000455879 ELMO1-007 37244356-37343179 protein_coding
  ENST00000463390 ELMO1-009 37269454-37448856 retained_intron
  ENST00000464262 ELMO1-016 36870393-36986116 processed_transcript
  ENST00000472359 ELMO1-021 36894922-37197223 processed_transcript
  ENST00000479447 ELMO1-004 37429257-37448950 processed_transcript
  ENST00000487336 ELMO1-020 37133006-37224919 retained_intron
  ENST00000487843 ELMO1-018 36855498-36986149 processed_transcript
  ENST00000497024 ELMO1-017 36855367-36862150 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310758ENST00000396040ENST00000396045ENST00000420636ENST00000442504ENST00000448602ENST00000455879
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310758 5.924±0.00 N/A N/A 8.629±4.68 1.714±0.24 1.553±0.15 0.801±0.01 0.447±0.00 1.200±0.05 2.252±0.50 0.725±0.24 2.087±1.37 3.351±0.76 1.014±0.43
ENST00000396040 5.890±0.00 10.177±0.00 N/A 45.964±0.00 3.886±0.00 3.442±0.00 2.246±0.00 2.941±0.00 4.332±0.00 10.595±0.00 2.189±0.00 2.563±0.46 5.809±0.37 2.376±1.30
ENST00000396045 N/A N/A N/A 9.790±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000420636 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.167±0.00 2.208±0.00
ENST00000442504 N/A N/A 0.354±0.00 N/A 1.478±0.00 N/A N/A N/A 1.446±0.00 1.985±0.00 0.269±0.00 0.492±0.00 2.431±0.26 1.207±0.00
ENST00000448602 5.112±0.00 N/A 0.672±0.00 N/A 2.180±0.00 3.059±0.00 N/A 2.112±0.00 N/A 2.982±0.03 0.597±0.00 0.878±0.00 N/A N/A
ENST00000455879 N/A N/A 3.658±0.00 N/A 8.124±0.00 6.177±0.00 1.244±0.00 5.268±0.00 11.734±0.00 21.900±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0006909 IEA phagocytosis
GO:0006911 IGI phagocytosis, engulfment
GO:0006915 NAS apoptotic process
GO:0006928 IGI cellular component movement
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016601 IGI Rac protein signal transduction
GO:0017124 IPI SH3 domain binding
GO:0030029 IEA actin filament-based process
GO:0030036 IGI actin cytoskeleton organization
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS innate immune response
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019258 elmo1 engulfment and cell motility 1 (ced-12 homolog, C. elegans) protein_coding Danio_rerio
ENSDARG00000055400 ELMO1 (2 of 2) engulfment and cell motility 1 protein_coding Danio_rerio
ENSMUSG00000041112 Elmo1 engulfment and cell motility 1 protein_coding Mus_musculus

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