C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zinc and ring finger 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041961 Znrf3 10090 - 11:5276324-5444847 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000109867 Znrf3-001 5276324-5444847 protein_coding
  ENSMUST00000143746 Znrf3-003 5288797-5444847 protein_coding
  ENSMUST00000172492 Znrf3-002 5278602-5381740 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000109867ENSMUST00000143746ENSMUST00000172492
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000109867 0.306±0.14 2.473±0.16 0.799±0.00 0.154±0.00 0.817±0.00 1.490±0.74 0.187±0.00 0.432±0.08 0.383±0.04 1.800±0.51 0.312±0.16 1.734±0.70 0.200±0.05 1.346±0.17
ENSMUST00000143746 N/A 2.090±0.41 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.297±0.00 N/A N/A
ENSMUST00000172492 1.078±0.65 5.091±1.31 N/A 0.289±0.12 0.867±0.37 1.661±0.32 0.456±0.18 0.640±0.00 0.875±0.43 3.322±0.54 0.335±0.08 2.636±0.98 0.221±0.11 2.562±1.20

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005109 IEA frizzled binding
GO:0005887 ISS integral component of plasma membrane
GO:0006511 ISS ubiquitin-dependent protein catabolic process
GO:0008270 IEA zinc ion binding
GO:0016567 ISS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0038018 ISS Wnt receptor catabolic process
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060071 IMP Wnt signaling pathway, planar cell polarity pathway
GO:0072089 IMP stem cell proliferation
GO:0090090 ISS negative regulation of canonical Wnt signaling pathway
GO:2000051 ISS negative regulation of non-canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062573 znrf3 zinc and ring finger 3 protein_coding Danio_rerio
ENSG00000183579 ZNRF3 zinc and ring finger 3 protein_coding Homo_sapiens

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