C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zinc and ring finger 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183579 ZNRF3 9606 + 22:28883592-29057487 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000402174 ZNRF3-002 28917389-29053685 protein_coding
  ENST00000406323 ZNRF3-003 28987052-29053965 protein_coding
  ENST00000544604 ZNRF3-001 28883592-29057487 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000544604
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000544604 0.983±0.00 2.582±0.00 2.553±1.17 2.479±0.00 2.011±0.00 0.411±0.00 4.449±2.85 1.295±0.00 1.962±0.00 3.122±0.01 2.564±0.58 3.938±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TU CIL_0004TU_0002 CGP 22:28794555-29057487

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005887 IDA integral component of plasma membrane
GO:0006511 IMP ubiquitin-dependent protein catabolic process
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0038018 IMP Wnt receptor catabolic process
GO:0046872 IEA metal ion binding
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060071 IEA Wnt signaling pathway, planar cell polarity pathway
GO:0072089 ISS stem cell proliferation
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:2000051 IMP negative regulation of non-canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062573 znrf3 zinc and ring finger 3 protein_coding Danio_rerio
ENSMUSG00000041961 Znrf3 zinc and ring finger 3 protein_coding Mus_musculus

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