C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenosine A1 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042429 Adora1 10090 - 1:134199223-134235431 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038191 Adora1-002 134201349-134235397 protein_coding
  ENSMUST00000086465 Adora1-001 134199225-134235431 protein_coding
  ENSMUST00000169927 Adora1-201 134199223-134234578 protein_coding
  ENSMUST00000187631 Adora1-004 134203397-134235364 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038191ENSMUST00000086465ENSMUST00000169927ENSMUST00000187631
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038191 8.399±3.54 40.760±4.84 0.949±0.00 0.889±0.26 6.459±1.29 0.561±0.18 2.539±0.50 1.708±0.28 1.839±1.18 1.053±0.10 N/A 2.781±0.67 0.426±0.23 2.215±0.28
ENSMUST00000086465 N/A N/A N/A 3.235±2.24 6.533±0.00 0.561±0.24 0.859±0.00 0.714±0.13 0.841±0.78 N/A N/A 6.002±3.75 0.655±0.49 2.910±1.23
ENSMUST00000169927 12.481±6.43 57.061±9.72 1.018±0.18 3.412±3.23 10.339±2.47 0.597±0.20 1.734±0.65 2.697±0.36 1.659±1.36 1.614±0.14 3.042±1.27 3.923±0.57 0.288±0.06 3.166±1.36
ENSMUST00000187631 N/A 81.648±9.90 N/A N/A 10.774±0.00 1.291±0.13 3.422±0.93 3.463±0.25 3.646±1.75 2.288±0.24 N/A 5.490±0.68 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001659 IEA temperature homeostasis
GO:0001664 IEA G-protein coupled receptor binding
GO:0001666 IEA response to hypoxia
GO:0001883 IEA purine nucleoside binding
GO:0001973 IEA adenosine receptor signaling pathway
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0002674 IEA negative regulation of acute inflammatory response
GO:0002686 IGI negative regulation of leukocyte migration
GO:0002793 IEA positive regulation of peptide secretion
GO:0003093 IMP regulation of glomerular filtration
GO:0004629 IEA phospholipase C activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006612 IEA protein targeting to membrane
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0008285 IEA negative regulation of cell proliferation
GO:0012505 IEA endomembrane system
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014069 IEA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0016042 IEA lipid catabolic process
GO:0016323 IEA basolateral plasma membrane
GO:0030425 IEA dendrite
GO:0030673 IEA axolemma
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0032244 IEA positive regulation of nucleoside transport
GO:0032279 IEA asymmetric synapse
GO:0032795 IEA heterotrimeric G-protein binding
GO:0032900 IEA negative regulation of neurotrophin production
GO:0035307 IEA positive regulation of protein dephosphorylation
GO:0035814 IEA negative regulation of renal sodium excretion
GO:0042321 IEA negative regulation of circadian sleep/wake cycle, sleep
GO:0042323 IEA negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0042734 IEA presynaptic membrane
GO:0043025 IEA neuronal cell body
GO:0043066 IEA negative regulation of apoptotic process
GO:0043195 IEA terminal bouton
GO:0043197 IDA dendritic spine
GO:0043268 IEA positive regulation of potassium ion transport
GO:0044297 IEA cell body
GO:0045202 IDA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045741 IEA positive regulation of epidermal growth factor-activated receptor activity
GO:0045776 IEA negative regulation of blood pressure
GO:0045777 IEA positive regulation of blood pressure
GO:0045822 IEA negative regulation of heart contraction
GO:0045908 IEA negative regulation of vasodilation
GO:0046888 IEA negative regulation of hormone secretion
GO:0046982 IEA protein heterodimerization activity
GO:0048167 IEA regulation of synaptic plasticity
GO:0048786 IEA presynaptic active zone
GO:0050728 IGI negative regulation of inflammatory response
GO:0050890 IEA cognition
GO:0050965 IEA detection of temperature stimulus involved in sensory perception of pain
GO:0050995 IEA negative regulation of lipid catabolic process
GO:0051930 IMP regulation of sensory perception of pain
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0055118 IEA negative regulation of cardiac muscle contraction
GO:0060079 IDA regulation of excitatory postsynaptic membrane potential
GO:0060087 IEA relaxation of vascular smooth muscle
GO:0070256 IGI negative regulation of mucus secretion
GO:1900453 IGI negative regulation of long term synaptic depression

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070056 ADORA1 (1 of 2) adenosine A1 receptor protein_coding Danio_rerio
ENSDARG00000075694 adora1 adenosine A1 receptor protein_coding Danio_rerio
ENSG00000163485 ADORA1 adenosine A1 receptor protein_coding Homo_sapiens

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