C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenosine A1 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163485 ADORA1 9606 + 1:203090654-203167405 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309502 ADORA1-002 203090654-203167404 protein_coding
  ENST00000337894 ADORA1-201 203127708-203167405 protein_coding
  ENST00000367235 ADORA1-003 203128306-203166749 protein_coding
  ENST00000367236 ADORA1-001 203127065-203167405 protein_coding
  ENST00000464019 ADORA1-004 203129634-203165741 processed_transcript
  ENST00000467253 ADORA1-006 203152646-203166115 processed_transcript
  ENST00000472535 ADORA1-005 203150632-203166749 processed_transcript
  ENST00000618295 ADORA1-202 203128373-203166062 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309502ENST00000337894ENST00000367235ENST00000464019ENST00000467253ENST00000472535ENST00000618295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309502 N/A N/A N/A 2.516±0.00 0.042±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000337894 0.643±0.00 0.383±0.00 0.194±0.00 12.402±11.39 2.556±2.51 0.047±0.00 0.625±0.48 1.844±0.00 0.060±0.00 0.255±0.00 0.186±0.00 0.413±0.12 1.497±0.37 6.530±1.85
ENST00000367235 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.281±0.19 1.186±0.07 3.335±0.00
ENST00000464019 N/A N/A N/A N/A N/A N/A N/A N/A 0.859±0.00 N/A N/A N/A N/A N/A
ENST00000467253 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.171±0.00 N/A N/A
ENST00000472535 N/A N/A N/A N/A N/A 0.344±0.00 0.176±0.00 N/A N/A N/A N/A 0.124±0.00 N/A N/A
ENST00000618295 N/A N/A 0.365±0.00 N/A N/A N/A 0.250±0.00 N/A 0.337±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001659 IEA temperature homeostasis
GO:0001664 IEA G-protein coupled receptor binding
GO:0001666 IEA response to hypoxia
GO:0001883 IEA purine nucleoside binding
GO:0001973 IEA adenosine receptor signaling pathway
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0002674 IEA negative regulation of acute inflammatory response
GO:0002686 IEA negative regulation of leukocyte migration
GO:0002793 IEA positive regulation of peptide secretion
GO:0003093 IEA regulation of glomerular filtration
GO:0004629 IEA phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006612 IEA protein targeting to membrane
GO:0006909 TAS phagocytosis
GO:0006954 TAS inflammatory response
GO:0007165 TAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007399 TAS nervous system development
GO:0008285 IEA negative regulation of cell proliferation
GO:0012505 IEA endomembrane system
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014069 IEA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0016042 IEA lipid catabolic process
GO:0016323 IEA basolateral plasma membrane
GO:0030425 IEA dendrite
GO:0030673 IEA axolemma
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0032244 IEA positive regulation of nucleoside transport
GO:0032279 IEA asymmetric synapse
GO:0032795 IEA heterotrimeric G-protein binding
GO:0032900 IEA negative regulation of neurotrophin production
GO:0035307 IEA positive regulation of protein dephosphorylation
GO:0035814 IEA negative regulation of renal sodium excretion
GO:0042321 IEA negative regulation of circadian sleep/wake cycle, sleep
GO:0042323 IEA negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0042734 IEA presynaptic membrane
GO:0043025 IEA neuronal cell body
GO:0043066 IEA negative regulation of apoptotic process
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0043268 IEA positive regulation of potassium ion transport
GO:0044297 IEA cell body
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045741 IEA positive regulation of epidermal growth factor-activated receptor activity
GO:0045776 IEA negative regulation of blood pressure
GO:0045777 IEA positive regulation of blood pressure
GO:0045822 IEA negative regulation of heart contraction
GO:0045908 IEA negative regulation of vasodilation
GO:0046888 IEA negative regulation of hormone secretion
GO:0046982 IEA protein heterodimerization activity
GO:0048167 IEA regulation of synaptic plasticity
GO:0048786 IEA presynaptic active zone
GO:0050728 IEA negative regulation of inflammatory response
GO:0050890 IEA cognition
GO:0050965 IEA detection of temperature stimulus involved in sensory perception of pain
GO:0050995 IEA negative regulation of lipid catabolic process
GO:0051930 IEA regulation of sensory perception of pain
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0055118 IEA negative regulation of cardiac muscle contraction
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060087 IEA relaxation of vascular smooth muscle
GO:0070256 IEA negative regulation of mucus secretion
GO:0097190 TAS apoptotic signaling pathway
GO:1900453 IEA negative regulation of long term synaptic depression

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070056 ADORA1 (1 of 2) adenosine A1 receptor protein_coding Danio_rerio
ENSDARG00000075694 adora1 adenosine A1 receptor protein_coding Danio_rerio
ENSMUSG00000042429 Adora1 adenosine A1 receptor protein_coding Mus_musculus

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