C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042487 Leo1 10090 + 9:75441524-75466432 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048937 Leo1-201 75441524-75466432 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048937
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048937 2.813±1.03 1.780±0.62 1.715±0.25 16.642±11.71 1.297±0.29 1.734±0.49 1.890±0.36 1.904±0.38 3.667±1.64 1.819±0.87 6.794±1.38 9.121±12.73 29.353±27.32 35.270±46.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00072B CIL_00072B_0002 CGP 9:75441524-75559657

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001711 IMP endodermal cell fate commitment
GO:0005515 IPI protein binding
GO:0006351 IEA transcription, DNA-templated
GO:0006378 ISS mRNA polyadenylation
GO:0010390 IEA histone monoubiquitination
GO:0016055 IEA Wnt signaling pathway
GO:0016593 ISS Cdc73/Paf1 complex
GO:0019827 IMP stem cell maintenance
GO:0031442 ISS positive regulation of mRNA 3'-end processing
GO:0032968 ISS positive regulation of transcription elongation from RNA polymerase II promoter
GO:0033523 IEA histone H2B ubiquitination
GO:0045638 ISS negative regulation of myeloid cell differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055357 leo1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000166477 LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Homo_sapiens

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