C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166477 LEO1 9606 - 15:51938025-51971806 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299601 LEO1-001 51938025-51971806 protein_coding
  ENST00000315141 LEO1-002 51938027-51971776 protein_coding
  ENST00000558949 LEO1-003 51953215-51955061 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000299601ENST00000315141
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000299601 8.364±0.00 1.581±0.00 4.789±1.79 3.904±1.58 6.006±1.81 2.850±0.00 6.746±3.66 5.327±1.97 1.861±0.00 8.124±4.00 5.500±2.38 7.945±0.02
ENST00000315141 N/A N/A N/A N/A N/A 0.831±0.00 N/A N/A 0.508±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001711 ISS endodermal cell fate commitment
GO:0005515 IPI protein binding
GO:0006351 IEA transcription, DNA-templated
GO:0006378 IMP mRNA polyadenylation
GO:0010390 IDA histone monoubiquitination
GO:0016055 IEA Wnt signaling pathway
GO:0016593 IDA Cdc73/Paf1 complex
GO:0019827 IDA stem cell maintenance
GO:0031442 IMP positive regulation of mRNA 3'-end processing
GO:0032968 IDA positive regulation of transcription elongation from RNA polymerase II promoter
GO:0033523 IDA histone H2B ubiquitination
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055357 leo1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000042487 Leo1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Mus_musculus

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