C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dapper homolog 1, antagonist of beta-catenin (xenopus)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044548 Dact1 10090 + 12:71309884-71320107 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061273 Dact1-001 71309884-71320107 protein_coding
  ENSMUST00000150639 Dact1-002 71309984-71318894 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061273ENSMUST00000150639
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061273 1.397±0.12 4.768±0.07 7.675±5.22 1.221±0.41 0.494±0.04 0.677±0.20 0.723±0.20 0.193±0.07 1.123±0.21 0.415±0.17 4.904±3.74 0.636±0.16 0.520±0.07
ENSMUST00000150639 N/A N/A 0.462±0.00 0.675±0.00 N/A N/A N/A N/A N/A N/A 4.645±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001K6 CIL_0001K6_0002 CGP 12:71136848-71320107
CIL_0007Q5 CIL_0007Q5_0002 VISTA 12:71232268-71832268
CIL_0001K5 CIL_0001K5_0002 CGP 12:71309884-71992367

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001702 IMP gastrulation with mouth forming second
GO:0005080 IDA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0008013 ISS beta-catenin binding
GO:0030054 IEA cell junction
GO:0030177 ISS positive regulation of Wnt signaling pathway
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0030877 ISS beta-catenin destruction complex
GO:0031647 ISS regulation of protein stability
GO:0035412 ISS regulation of catenin import into nucleus
GO:0035413 ISS positive regulation of catenin import into nucleus
GO:0045202 IEA synapse
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0045732 IEA positive regulation of protein catabolic process
GO:0046329 ISS negative regulation of JNK cascade
GO:0048598 IMP embryonic morphogenesis
GO:0048619 IMP embryonic hindgut morphogenesis
GO:0048813 IGI dendrite morphogenesis
GO:0050808 IMP synapse organization
GO:0051018 ISS protein kinase A binding
GO:0070097 IDA delta-catenin binding
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:2000095 IGI regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000134 ISS negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039675 dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) protein_coding Danio_rerio
ENSG00000165617 DACT1 dishevelled-binding antagonist of beta-catenin 1 protein_coding Homo_sapiens

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