C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dishevelled-binding antagonist of beta-catenin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165617 DACT1 9606 + 14:58633967-58648321 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335867 DACT1-004 58638179-58647170 protein_coding
  ENST00000395153 DACT1-002 58638056-58648321 protein_coding
  ENST00000421793 DACT1-003 58634081-58645856 protein_coding
  ENST00000541264 DACT1-005 58638837-58647263 protein_coding
  ENST00000555845 DACT1-006 58633967-58645472 processed_transcript
  ENST00000556859 DACT1-007 58634068-58647200 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335867ENST00000395153ENST00000421793ENST00000556859
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335867 N/A N/A N/A N/A N/A N/A N/A N/A 0.078±0.00 N/A 0.449±0.00 N/A N/A N/A
ENST00000395153 0.925±0.00 3.940±0.00 0.369±0.00 1.061±0.39 1.685±0.17 3.494±0.00 0.780±0.00 1.247±0.00 0.185±0.00 11.994±0.00 0.521±0.00 5.733±6.01 4.021±1.00 7.077±0.33
ENST00000421793 N/A N/A N/A N/A N/A N/A 0.194±0.00 N/A 1.235±0.00 0.817±0.00 0.440±0.00 N/A N/A N/A
ENST00000556859 N/A N/A N/A N/A N/A N/A N/A 0.306±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001K6 CIL_0001K6_0001 CGP 14:58427385-58648321
CIL_0007Q5 CIL_0007Q5_0001 VISTA 14:58571064-59171064
CIL_0001K5 CIL_0001K5_0001 CGP 14:58633967-59371405

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001702 IEA gastrulation with mouth forming second
GO:0005080 ISS protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0008013 IDA beta-catenin binding
GO:0016055 IEA Wnt signaling pathway
GO:0030054 IEA cell junction
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030877 IDA beta-catenin destruction complex
GO:0031647 IDA regulation of protein stability
GO:0035412 IMP regulation of catenin import into nucleus
GO:0035413 IMP positive regulation of catenin import into nucleus
GO:0045202 IEA synapse
GO:0045600 IEA positive regulation of fat cell differentiation
GO:0045732 IDA positive regulation of protein catabolic process
GO:0046329 IDA negative regulation of JNK cascade
GO:0048598 IEA embryonic morphogenesis
GO:0048619 ISS embryonic hindgut morphogenesis
GO:0048813 IEA dendrite morphogenesis
GO:0050808 IEA synapse organization
GO:0051018 IDA protein kinase A binding
GO:0070097 ISS delta-catenin binding
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:2000095 ISS regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039675 dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) protein_coding Danio_rerio
ENSMUSG00000044548 Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) protein_coding Mus_musculus

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