C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: toll-like receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044827 Tlr1 10090 - 5:64924811-64932761 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000059349 Tlr1-201 64924811-64932761 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059349
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059349 0.544±0.32 0.712±0.23 0.092±0.06 4.724±1.77 7.864±3.59 0.153±0.03 0.544±0.04 0.229±0.09 1.328±0.20 0.098±0.16 0.880±0.52 0.096±0.06 0.079±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A6 CIL_0007A6_0002 CGP 5:64924811-64960048

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0004888 NAS transmembrane signaling receptor activity
GO:0006952 IMP defense response
GO:0006954 IEA inflammatory response
GO:0007250 NAS activation of NF-kappaB-inducing kinase activity
GO:0016020 NAS membrane
GO:0016021 IEA integral component of membrane
GO:0034130 IEA toll-like receptor 1 signaling pathway
GO:0035354 IEA Toll-like receptor 1-Toll-like receptor 2 protein complex
GO:0042116 NAS macrophage activation
GO:0042495 NAS detection of triacyl bacterial lipopeptide
GO:0042497 NAS triacyl lipopeptide binding
GO:0042535 IMP positive regulation of tumor necrosis factor biosynthetic process
GO:0045087 IEA innate immune response
GO:0045335 NAS phagocytic vesicle
GO:0045410 IMP positive regulation of interleukin-6 biosynthetic process
GO:0046982 IEA protein heterodimerization activity
GO:0050707 IEA regulation of cytokine secretion
GO:0071727 IEA cellular response to triacyl bacterial lipopeptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043032 tlr1 toll-like receptor 1 protein_coding Danio_rerio
ENSG00000174125 TLR1 toll-like receptor 1 protein_coding Homo_sapiens

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