C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: toll-like receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174125 TLR1 9606 - 4:38790677-38856817 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308979 TLR1-201 38796257-38804791 protein_coding
  ENST00000502213 TLR1-001 38796283-38804376 protein_coding
  ENST00000505744 TLR1-003 38790848-38804819 processed_transcript
  ENST00000505940 TLR1-005 38798349-38804851 protein_coding
  ENST00000506146 TLR1-004 38798686-38856817 protein_coding
  ENST00000508364 TLR1-007 38798761-38805578 protein_coding
  ENST00000508535 TLR1-008 38800870-38805533 processed_transcript
  ENST00000509754 TLR1-009 38800472-38804789 processed_transcript
  ENST00000510552 TLR1-010 38790677-38794633 processed_transcript
  ENST00000515861 TLR1-006 38798561-38804916 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308979ENST00000502213ENST00000505940ENST00000510552
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308979 N/A 2.891±0.00 N/A N/A N/A N/A N/A N/A 0.251±0.00 N/A N/A 1.559±0.00 1.088±0.49 0.381±0.00
ENST00000502213 0.734±0.00 N/A 1.334±0.00 1.000±0.00 1.148±0.71 0.593±0.37 0.247±0.07 1.160±0.25 N/A 1.105±0.00 N/A N/A 0.824±0.00 0.103±0.02
ENST00000505940 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.191±0.00 N/A N/A N/A
ENST00000510552 N/A N/A N/A N/A N/A 0.198±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007A6 CIL_0007A6_0001 CGP 4:38790677-38856817

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002224 IEA toll-like receptor signaling pathway
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0004872 TAS receptor activity
GO:0004888 IEA:NAS transmembrane signaling receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006952 IEA defense response
GO:0006954 IEA inflammatory response
GO:0006955 TAS:IEA immune response
GO:0007165 TAS:IEA signal transduction
GO:0016020 NAS membrane
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0034130 IEA toll-like receptor 1 signaling pathway
GO:0035354 IDA Toll-like receptor 1-Toll-like receptor 2 protein complex
GO:0042116 IEA:NAS macrophage activation
GO:0042495 IEA:IDA detection of triacyl bacterial lipopeptide
GO:0042535 ISS positive regulation of tumor necrosis factor biosynthetic process
GO:0045087 IEA innate immune response
GO:0045410 ISS positive regulation of interleukin-6 biosynthetic process
GO:0046982 IDA protein heterodimerization activity
GO:0050707 IEA regulation of cytokine secretion
GO:0071727 IDA cellular response to triacyl bacterial lipopeptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043032 tlr1 toll-like receptor 1 protein_coding Danio_rerio
ENSMUSG00000044827 Tlr1 toll-like receptor 1 protein_coding Mus_musculus

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