C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled homolog 5 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045005 Fzd5 10090 - 1:64730558-64737751 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063982 Fzd5-001 64730558-64737751 protein_coding
  ENSMUST00000116133 Fzd5-002 64734469-64737749 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063982ENSMUST00000116133
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063982 1.413±0.43 1.903±0.36 1.623±0.25 0.297±0.15 0.625±0.21 12.670±0.79 0.521±0.19 2.104±0.65 1.515±0.94 4.515±0.63 0.319±0.08 1.379±0.39 2.795±1.13 0.441±0.06
ENSMUST00000116133 1.300±0.23 7.121±1.51 N/A 0.278±0.09 1.881±0.59 29.354±9.90 0.492±0.19 2.229±0.97 1.081±0.81 6.728±1.49 0.129±0.00 6.307±0.80 N/A 0.407±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YT CIL_0006YT_0002 CGP 1:64690455-64737751
CIL_0006YS CIL_0006YS_0002 CGP 1:64730558-64956824

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000578 IEA embryonic axis specification
GO:0001525 IMP angiogenesis
GO:0001944 IMP vasculature development
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005737 IBA cytoplasm
GO:0005769 IDA early endosome
GO:0005794 IDA Golgi apparatus
GO:0005886 IBA plasma membrane
GO:0005923 IDA tight junction
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008285 IMP negative regulation of cell proliferation
GO:0008406 IBA gonad development
GO:0008595 IEA anterior/posterior axis specification, embryo
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016055 IGI Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0019901 IEA protein kinase binding
GO:0030165 IBA PDZ domain binding
GO:0031076 IMP embryonic camera-type eye development
GO:0031077 IMP post-embryonic camera-type eye development
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0033077 IMP T cell differentiation in thymus
GO:0042813 IBA Wnt-activated receptor activity
GO:0042995 IBA cell projection
GO:0043507 IDA positive regulation of JUN kinase activity
GO:0044332 IEA Wnt signaling pathway involved in dorsal/ventral axis specification
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IMP cell maturation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0060061 IEA Spemann organizer formation
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060561 IMP apoptotic process involved in morphogenesis
GO:0060670 IMP branching involved in labyrinthine layer morphogenesis
GO:0060715 IMP syncytiotrophoblast cell differentiation involved in labyrinthine layer development
GO:0060716 IMP labyrinthine layer blood vessel development
GO:0060718 IMP chorionic trophoblast cell differentiation
GO:0060828 IMP regulation of canonical Wnt signaling pathway
GO:0071219 IEA cellular response to molecule of bacterial origin
GO:1901382 IMP regulation of chorionic trophoblast cell proliferation
GO:2000810 IMP regulation of tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025420 fzd5 frizzled homolog 5 protein_coding Danio_rerio
ENSG00000163251 FZD5 frizzled class receptor 5 protein_coding Homo_sapiens

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