C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: multiple EGF-like-domains 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045039 Megf8 10090 + 7:25317164-25365917 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000128119 Megf8-001 25317164-25365917 protein_coding
  ENSMUST00000153077 Megf8-002 25345981-25365914 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000128119ENSMUST00000153077
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000128119 6.903±0.68 18.382±4.52 4.459±0.43 11.369±1.65 8.395±3.92 8.274±2.03 4.167±0.63 4.970±1.28 0.808±0.49 10.390±0.73 3.766±0.93 19.428±8.63 2.694±1.65 3.426±1.62
ENSMUST00000153077 5.741±1.32 12.708±2.89 7.282±0.30 14.735±7.49 4.349±0.93 5.027±0.88 3.105±0.00 4.242±0.88 0.679±0.34 6.124±1.82 1.935±0.39 9.996±3.46 2.537±0.70 1.889±1.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005V6 CIL_0005V6_0002 CGP 7:25306106-25365917
CIL_00053T CIL_00053T_0002 CGP 7:25317164-25369724

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003143 IMP embryonic heart tube morphogenesis
GO:0003674 ND molecular_function
GO:0004872 IEA receptor activity
GO:0005509 IEA calcium ion binding
GO:0005634 IDA nucleus
GO:0010468 IMP regulation of gene expression
GO:0016021 IEA integral component of membrane
GO:0030326 IMP embryonic limb morphogenesis
GO:0030509 IGI BMP signaling pathway
GO:0035108 IEA limb morphogenesis
GO:0042074 IEA cell migration involved in gastrulation
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0048842 IMP positive regulation of axon extension involved in axon guidance
GO:0055113 IEA epiboly involved in gastrulation with mouth forming second
GO:0060971 IMP embryonic heart tube left/right pattern formation
GO:0060972 IMP left/right pattern formation
GO:0061371 IMP determination of heart left/right asymmetry
GO:0070062 IEA extracellular vesicular exosome
GO:0071907 IMP determination of digestive tract left/right asymmetry
GO:0097094 IEA craniofacial suture morphogenesis
GO:0097155 IMP fasciculation of sensory neuron axon
GO:1900164 ISO nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079751 megf8 multiple EGF-like-domains 8 protein_coding Danio_rerio
ENSG00000105429 MEGF8 multiple EGF-like-domains 8 protein_coding Homo_sapiens

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