C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sprouty-related, EVH1 domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045671 Spred2 10090 + 11:19924375-20024026 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000093298 Spred2-201 19924442-20022577 protein_coding
  ENSMUST00000093299 Spred2-001 19924375-20024026 protein_coding
  ENSMUST00000123036 Spred2-002 19954570-20018133 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000093298ENSMUST00000093299
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093298 N/A 6.863±3.38 4.061±0.00 2.637±0.93 4.271±0.82 3.759±1.37 1.867±0.36 1.980±0.00 0.768±0.42 3.004±1.23 0.477±0.06 2.190±0.85 1.572±0.22 0.477±0.22
ENSMUST00000093299 4.152±2.07 6.033±1.56 10.278±0.00 6.138±0.77 3.653±2.03 11.891±1.72 0.789±0.00 4.326±1.24 1.222±0.70 5.352±0.57 N/A 3.252±0.17 2.366±0.63 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000OI CIL_0000OI_0002 CGP 11:19924375-20112913

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IMP inactivation of MAPK activity
GO:0005173 IPI stem cell factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0010801 IDA negative regulation of peptidyl-threonine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0030291 IDA protein serine/threonine kinase inhibitor activity
GO:0031410 IDA cytoplasmic vesicle
GO:0043517 IDA positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 IDA regulation of protein deacetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008372 spred2b sprouty-related, EVH1 domain containing 2b protein_coding Danio_rerio
ENSDARG00000052435 spred2a sprouty-related, EVH1 domain containing 2a protein_coding Danio_rerio
ENSG00000198369 SPRED2 sprouty-related, EVH1 domain containing 2 protein_coding Homo_sapiens

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