C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sprouty-related, EVH1 domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198369 SPRED2 9606 - 2:65310851-65432637 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356388 SPRED2-001 65310851-65432177 protein_coding
  ENST00000421087 SPRED2-002 65313703-65334773 protein_coding
  ENST00000426832 SPRED2-004 65332204-65344799 nonsense_mediated_decay
  ENST00000427238 SPRED2-005 65344196-65344786 protein_coding
  ENST00000440972 SPRED2-007 65334629-65432637 protein_coding
  ENST00000443619 SPRED2-008 65312993-65366650 protein_coding
  ENST00000452315 SPRED2-006 65313505-65377750 protein_coding
  ENST00000474228 SPRED2-003 65316734-65366752 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356388ENST00000427238ENST00000440972ENST00000443619ENST00000474228
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356388 22.068±0.00 4.294±0.00 0.334±0.00 3.268±1.78 5.447±0.00 3.905±2.53 2.811±2.43 4.877±2.63 2.407±0.72 5.774±5.25 1.918±1.01 5.335±2.03 7.411±1.93 3.774±2.80
ENST00000427238 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.763±0.00
ENST00000440972 N/A N/A 1.273±0.00 N/A N/A N/A N/A N/A N/A N/A 1.773±0.00 N/A N/A N/A
ENST00000443619 N/A N/A N/A N/A N/A N/A 0.300±0.00 N/A 0.802±0.00 N/A N/A N/A N/A N/A
ENST00000474228 N/A N/A N/A N/A N/A N/A N/A 1.226±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002N3 CIL_0002N3_0002 CGP 2:65227753-65432637

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0005173 ISS stem cell factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0009966 IEA regulation of signal transduction
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0016020 IEA membrane
GO:0019901 IPI protein kinase binding
GO:0030291 ISS protein serine/threonine kinase inhibitor activity
GO:0031410 IEA cytoplasmic vesicle
GO:0043517 ISS positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090311 ISS regulation of protein deacetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008372 spred2b sprouty-related, EVH1 domain containing 2b protein_coding Danio_rerio
ENSDARG00000052435 spred2a sprouty-related, EVH1 domain containing 2a protein_coding Danio_rerio
ENSMUSG00000045671 Spred2 sprouty-related, EVH1 domain containing 2 protein_coding Mus_musculus

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