C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 21
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045680 Tcf21 10090 - 10:22817279-22820128 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049930 Tcf21-201 22817279-22820128 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049930
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049930 41.162±26.21 9.539±0.62 137.488±7.41 0.248±0.07 0.061±0.03 61.896±4.91 11.632±2.26 57.248±5.36 6.110±1.52 100.906±17.50 0.042±0.02 60.976±17.80 3.707±2.24 4.451±2.19

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001657 IMP ureteric bud development
GO:0001658 IMP branching involved in ureteric bud morphogenesis
GO:0001763 IMP morphogenesis of a branching structure
GO:0001822 IMP kidney development
GO:0001944 IMP vasculature development
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007530 IMP sex determination
GO:0007548 IMP sex differentiation
GO:0009887 IMP organ morphogenesis
GO:0014707 IGI branchiomeric skeletal muscle development
GO:0030855 IMP epithelial cell differentiation
GO:0031063 IC regulation of histone deacetylation
GO:0032835 IMP glomerulus development
GO:0042826 IPI histone deacetylase binding
GO:0043425 IEA bHLH transcription factor binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IPI protein dimerization activity
GO:0048286 IMP lung alveolus development
GO:0048536 IMP spleen development
GO:0048557 ISS embryonic digestive tract morphogenesis
GO:0048608 IMP reproductive structure development
GO:0048732 ISS gland development
GO:0050681 IPI androgen receptor binding
GO:0060008 ISS Sertoli cell differentiation
GO:0060021 IGI palate development
GO:0060425 IMP lung morphogenesis
GO:0060426 IMP lung vasculature development
GO:0060435 IMP bronchiole development
GO:0060539 IGI diaphragm development
GO:0060541 IMP respiratory system development
GO:0060766 IDA negative regulation of androgen receptor signaling pathway
GO:0070888 IDA E-box binding
GO:0072162 IMP metanephric mesenchymal cell differentiation
GO:0072277 IMP metanephric glomerular capillary formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036869 tcf21 transcription factor 21 protein_coding Danio_rerio
ENSG00000118526 TCF21 transcription factor 21 protein_coding Homo_sapiens

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