C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 21
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118526 TCF21 9606 + 6:133889138-133895553 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237316 TCF21-002 133889335-133895553 protein_coding
  ENST00000367882 TCF21-001 133889138-133895553 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000237316ENST00000367882
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000237316 0.314±0.00 N/A N/A N/A 2.882±0.77 N/A 3.683±3.05 0.204±0.00 4.229±0.00 2.549±1.97 14.875±0.00 1.508±0.08
ENST00000367882 0.190±0.00 0.258±0.00 4.206±0.00 0.696±0.00 2.819±1.92 0.798±0.00 3.501±0.00 1.457±1.27 22.462±17.99 7.780±7.11 27.336±9.42 3.702±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014N CIL_00014N_0002 CGP 6:133240598-133895553
CIL_00014M CIL_00014M_0002 CGP 6:133889138-133990432

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001657 ISS ureteric bud development
GO:0001658 ISS branching involved in ureteric bud morphogenesis
GO:0001763 ISS morphogenesis of a branching structure
GO:0001822 ISS kidney development
GO:0001944 ISS vasculature development
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007530 ISS sex determination
GO:0007548 IEA sex differentiation
GO:0009887 IEA organ morphogenesis
GO:0014707 ISS branchiomeric skeletal muscle development
GO:0030855 ISS epithelial cell differentiation
GO:0032835 ISS glomerulus development
GO:0042826 IEA histone deacetylase binding
GO:0043425 IPI bHLH transcription factor binding
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046983 ISS:IEA protein dimerization activity
GO:0048286 ISS lung alveolus development
GO:0048536 ISS spleen development
GO:0048557 ISS embryonic digestive tract morphogenesis
GO:0048608 ISS reproductive structure development
GO:0048732 ISS gland development
GO:0050681 ISS androgen receptor binding
GO:0060008 ISS Sertoli cell differentiation
GO:0060021 ISS palate development
GO:0060425 ISS lung morphogenesis
GO:0060426 ISS lung vasculature development
GO:0060435 ISS bronchiole development
GO:0060539 ISS diaphragm development
GO:0060541 ISS respiratory system development
GO:0060766 ISS negative regulation of androgen receptor signaling pathway
GO:0070888 ISS E-box binding
GO:0072162 ISS metanephric mesenchymal cell differentiation
GO:0072277 ISS metanephric glomerular capillary formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036869 tcf21 transcription factor 21 protein_coding Danio_rerio
ENSMUSG00000045680 Tcf21 transcription factor 21 protein_coding Mus_musculus

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