C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000046470 Sox18 10090 - 2:181669836-181671640 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054491 Sox18-001 181669836-181671640 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054491
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054491 56.696±16.13 47.659±10.21 13.532±1.23 8.139±2.56 42.801±13.25 12.623±0.77 34.991±8.07 22.924±1.58 4.204±1.83 146.071±8.68 6.896±1.65 53.204±19.03 6.674±1.48 2.041±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003V3 CIL_0003V3_0002 CGP 2:181669836-181688071

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IGI angiogenesis
GO:0001568 IMP blood vessel development
GO:0001570 IGI vasculogenesis
GO:0001701 IMP in utero embryonic development
GO:0001942 IMP hair follicle development
GO:0001944 IMP vasculature development
GO:0001945 IMP lymph vessel development
GO:0001946 IMP lymphangiogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007507 IMP heart development
GO:0022405 IEA hair cycle process
GO:0035050 IGI embryonic heart tube development
GO:0042789 IEA mRNA transcription from RNA polymerase II promoter
GO:0043534 IEA blood vessel endothelial cell migration
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048469 IDA cell maturation
GO:0048866 IDA stem cell fate specification
GO:0060214 IGI endocardium formation
GO:0060836 IMP lymphatic endothelial cell differentiation
GO:0060956 IGI endocardial cell differentiation
GO:0061028 IEA establishment of endothelial barrier
GO:0072091 IDA regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058598 sox18 SRY-box containing gene 18 protein_coding Danio_rerio
ENSG00000203883 SOX18 SRY (sex determining region Y)-box 18 protein_coding Homo_sapiens

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