C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: toll-like receptor adaptor molecule 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047123 Ticam1 10090 - 17:56269319-56276786 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000058136 Ticam1-001 56269319-56276786 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000058136
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000058136 5.907±1.64 17.977±1.62 1.302±0.00 9.203±1.43 16.347±7.71 5.031±0.71 11.741±0.91 7.824±2.79 5.880±1.64 0.811±0.24 9.950±3.66 6.514±2.83 1.156±0.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00028H CIL_00028H_0002 CGP 17:56256793-56276786
CIL_00028M CIL_00028M_0002 CGP 17:56269319-56290511

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002281 IMP macrophage activation involved in immune response
GO:0002756 IMP MyD88-independent toll-like receptor signaling pathway
GO:0005515 IPI protein binding
GO:0006954 IEA inflammatory response
GO:0019901 IEA protein kinase binding
GO:0030890 IMP positive regulation of B cell proliferation
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031663 IMP lipopolysaccharide-mediated signaling pathway
GO:0032092 IDA positive regulation of protein binding
GO:0032481 IMP positive regulation of type I interferon production
GO:0032496 IMP response to lipopolysaccharide
GO:0032755 IMP positive regulation of interleukin-6 production
GO:0032760 IMP positive regulation of tumor necrosis factor production
GO:0032816 IMP positive regulation of natural killer cell activation
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 IMP response to exogenous dsRNA
GO:0043496 IMP regulation of protein homodimerization activity
GO:0045080 IGI positive regulation of chemokine biosynthetic process
GO:0045087 IEA innate immune response
GO:0045359 IMP positive regulation of interferon-beta biosynthetic process
GO:0045429 IMP positive regulation of nitric oxide biosynthetic process
GO:0050871 IMP positive regulation of B cell activation
GO:0051092 IGI positive regulation of NF-kappaB transcription factor activity
GO:0051607 IMP defense response to virus
GO:0097190 IMP apoptotic signaling pathway
GO:0097342 IEA ripoptosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042714 ticam1 toll-like receptor adaptor molecule 1 protein_coding Danio_rerio
ENSDARG00000086136 ticam1 toll-like receptor adaptor molecule 1 protein_coding Danio_rerio
ENSG00000127666 TICAM1 toll-like receptor adaptor molecule 1 protein_coding Homo_sapiens

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