C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049583 Grm5 10090 + 7:87602544-88134907 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000107263 Grm5-201 87602544-88130869 protein_coding
  ENSMUST00000125009 Grm5-001 87803815-88134907 protein_coding
  ENSMUST00000138732 Grm5-003 87803815-87809620 processed_transcript
  ENSMUST00000155358 Grm5-002 87803815-88131654 protein_coding
  ENSMUST00000167164 Grm5-202 87602544-88130869 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastLiverLungMuscleOvaryPlacentaTestisENSMUST00000107263ENSMUST00000125009ENSMUST00000155358
Transcript ID Bladder Brain Breast Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107263 N/A 2.440±0.00 0.025±0.00 0.002±0.00 0.017±0.01 N/A 0.033±0.00 0.007±0.00 0.078±0.00
ENSMUST00000125009 0.002±0.00 2.932±2.03 0.012±0.00 0.003±0.00 N/A 0.004±0.00 0.004±0.00 0.002±0.00 N/A
ENSMUST00000155358 N/A N/A N/A 0.005±0.00 0.055±0.00 N/A N/A 0.009±0.00 0.208±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000185 IEA activation of MAPKKK activity
GO:0001639 TAS PLC activating G-protein coupled glutamate receptor activity
GO:0002029 IEA desensitization of G-protein coupled receptor protein signaling pathway
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007205 IBA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007206 TAS phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
GO:0007216 IBA G-protein coupled glutamate receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007612 IMP learning
GO:0007626 IGI locomotory behavior
GO:0008066 IBA glutamate receptor activity
GO:0014069 IBA postsynaptic density
GO:0016020 IEA membrane
GO:0031687 IEA A2A adenosine receptor binding
GO:0040013 IEA negative regulation of locomotion
GO:0043005 IDA neuron projection
GO:0043197 IEA dendritic spine
GO:0043198 IEA dendritic shaft
GO:0048169 IMP regulation of long-term neuronal synaptic plasticity
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0050890 IEA cognition
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0070062 IEA extracellular vesicular exosome
GO:0097449 IEA astrocyte projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004445 GRM5 (1 of 2) glutamate receptor, metabotropic 5 protein_coding Danio_rerio
ENSDARG00000075227 GRM5 (2 of 2) glutamate receptor, metabotropic 5 protein_coding Danio_rerio
ENSG00000168959 GRM5 glutamate receptor, metabotropic 5 protein_coding Homo_sapiens

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