C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168959 GRM5 9606 - 11:88504576-89065945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305432 GRM5-001 88507810-89048022 protein_coding
  ENST00000305447 GRM5-005 88507810-89048022 protein_coding
  ENST00000393294 GRM5-002 88984702-89065945 protein_coding
  ENST00000449371 GRM5-003 88911936-89047370 protein_coding
  ENST00000455756 GRM5-201 88504576-89063648 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartKidneyLungTestisENST00000305432ENST00000305447ENST00000393294
Transcript ID Brain Colon Heart Kidney Lung Testis
ENST00000305432 2.542±0.00 N/A 0.005±0.00 0.109±0.00 0.074±0.00 0.288±0.07
ENST00000305447 6.425±0.00 N/A N/A N/A N/A 0.185±0.00
ENST00000393294 N/A 0.011±0.00 0.006±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001JJ CIL_0001JJ_0002 CGP 11:88293592-89065945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000185 IEA activation of MAPKKK activity
GO:0002029 IEA desensitization of G-protein coupled receptor protein signaling pathway
GO:0004930 IMP:IEA G-protein coupled receptor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 IMP integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007205 IBA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007206 TAS phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
GO:0007216 IMP G-protein coupled glutamate receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007612 IEA learning
GO:0007626 IEA locomotory behavior
GO:0008066 IDA glutamate receptor activity
GO:0014069 IBA postsynaptic density
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031687 IEA A2A adenosine receptor binding
GO:0040013 IEA negative regulation of locomotion
GO:0043005 IEA neuron projection
GO:0043197 IEA dendritic spine
GO:0043198 IEA dendritic shaft
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0050890 IMP cognition
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0070062 IDA extracellular vesicular exosome
GO:0097449 IEA astrocyte projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004445 GRM5 (1 of 2) glutamate receptor, metabotropic 5 protein_coding Danio_rerio
ENSDARG00000075227 GRM5 (2 of 2) glutamate receptor, metabotropic 5 protein_coding Danio_rerio
ENSMUSG00000049583 Grm5 glutamate receptor, metabotropic 5 protein_coding Mus_musculus

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