C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lymphocyte transmembrane adaptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051998 Lax1 10090 - 1:133679091-133690108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000169295 Lax1-001 133679091-133690108 protein_coding
  ENSMUST00000189524 Lax1-002 133680470-133690086 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000169295ENSMUST00000189524
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000169295 0.558±0.34 0.152±0.04 1.425±0.47 0.139±0.01 4.805±2.37 2.578±0.95 0.162±0.05 0.328±0.18 0.495±0.35 0.648±0.19 0.370±0.63 0.620±0.13 0.480±0.17 0.321±0.08
ENSMUST00000189524 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.318±0.02 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W2 CIL_0008W2_0002 VISTA 1:133249313-133850886
CIL_00096T CIL_00096T_0002 VISTA 1:133444227-134045719

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IEA inactivation of MAPK activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019901 IEA protein kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0042113 IEA B cell activation
GO:0042169 IEA SH2 domain binding
GO:0046649 IMP lymphocyte activation
GO:0048305 IMP immunoglobulin secretion
GO:0050851 IMP antigen receptor-mediated signaling pathway
GO:0050868 IEA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000122188 LAX1 lymphocyte transmembrane adaptor 1 protein_coding Homo_sapiens

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