C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: contactin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053024 Cntn2 10090 - 1:132509427-132543256 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086521 Cntn2-001 132511782-132542939 protein_coding
  ENSMUST00000186487 Cntn2-002 132511778-132542890 retained_intron
  ENSMUST00000186530 Cntn2-006 132533657-132543256 protein_coding
  ENSMUST00000188065 Cntn2-004 132509427-132523393 nonsense_mediated_decay
  ENSMUST00000188143 Cntn2-008 132517001-132519157 retained_intron
  ENSMUST00000188943 Cntn2-007 132528999-132533884 protein_coding
  ENSMUST00000189528 Cntn2-005 132509427-132515637 nonsense_mediated_decay
  ENSMUST00000190601 Cntn2-003 132511792-132542865 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086521ENSMUST00000186487ENSMUST00000186530ENSMUST00000188065ENSMUST00000188143ENSMUST00000188943ENSMUST00000189528ENSMUST00000190601
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086521 0.031±0.00 N/A 0.077±0.00 20.367±5.58 0.167±0.02 0.061±0.03 1.136±0.21 0.013±0.00 0.004±0.00 N/A 0.026±0.01 0.410±0.22 0.028±0.00 0.020±0.00
ENSMUST00000186487 N/A 0.050±0.00 N/A 3.701±0.00 N/A N/A 0.327±0.00 N/A N/A N/A N/A 0.107±0.00 0.033±0.00 N/A
ENSMUST00000186530 N/A 0.701±0.00 N/A N/A N/A N/A N/A N/A N/A 0.594±0.00 N/A N/A N/A N/A
ENSMUST00000188065 0.032±0.00 0.014±0.01 N/A 16.635±0.00 0.145±0.09 0.146±0.08 0.412±0.01 0.031±0.02 0.032±0.00 0.028±0.00 N/A 0.211±0.10 0.022±0.00 0.017±0.00
ENSMUST00000188143 N/A N/A N/A N/A N/A 0.263±0.05 N/A 0.033±0.00 0.113±0.06 N/A N/A N/A N/A 0.097±0.00
ENSMUST00000188943 N/A 0.120±0.00 N/A N/A N/A 0.146±0.00 N/A 0.166±0.00 N/A N/A N/A 1.464±0.00 N/A N/A
ENSMUST00000189528 0.025±0.00 0.061±0.02 0.011±0.00 N/A 0.098±0.00 0.062±0.00 N/A N/A 0.033±0.02 0.035±0.00 N/A N/A 0.021±0.00 0.043±0.02
ENSMUST00000190601 0.008±0.00 0.021±0.00 N/A N/A 0.030±0.00 0.045±0.04 N/A 0.007±0.00 0.036±0.01 0.021±0.01 N/A 0.079±0.00 N/A 0.015±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0001764 IMP neuron migration
GO:0001948 IDA glycoprotein binding
GO:0005515 IPI protein binding
GO:0007155 IEA cell adhesion
GO:0007411 IGI axon guidance
GO:0007413 IMP axonal fasciculation
GO:0007612 IMP learning
GO:0007628 IMP adult walking behavior
GO:0008076 IDA voltage-gated potassium channel complex
GO:0009986 IDA cell surface
GO:0010769 IMP regulation of cell morphogenesis involved in differentiation
GO:0010954 IDA positive regulation of protein processing
GO:0021853 IMP cerebral cortex GABAergic interneuron migration
GO:0022010 IMP central nervous system myelination
GO:0030246 IDA carbohydrate binding
GO:0030424 IDA axon
GO:0031133 IMP regulation of axon diameter
GO:0031175 IGI neuron projection development
GO:0031225 IEA anchored component of membrane
GO:0031623 IDA receptor internalization
GO:0033268 IDA node of Ranvier
GO:0034613 IMP cellular protein localization
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043209 IDA myelin sheath
GO:0043621 IPI protein self-association
GO:0044224 IDA juxtaparanode region of axon
GO:0045163 IMP clustering of voltage-gated potassium channels
GO:0045665 IGI negative regulation of neuron differentiation
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:0048710 IMP regulation of astrocyte differentiation
GO:0060168 IMP positive regulation of adenosine receptor signaling pathway
GO:0071205 IMP protein localization to juxtaparanode region of axon
GO:0071206 IDA establishment of protein localization to juxtaparanode region of axon
GO:0097090 ISS presynaptic membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000472 cntn2 contactin 2 protein_coding Danio_rerio
ENSG00000184144 CNTN2 contactin 2 (axonal) protein_coding Homo_sapiens

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