C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TXK tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054892 Txk 10090 - 5:72695978-72752773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000113604 Txk-201 72695978-72752773 protein_coding
  ENSMUST00000169534 Txk-202 72695982-72736589 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000113604ENSMUST00000169534
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000113604 0.192±0.07 0.041±0.00 0.265±0.14 0.011±0.00 0.962±0.38 0.128±0.05 0.064±0.02 0.314±0.17 0.073±0.05 0.257±0.12 0.147±0.12 0.388±0.12 0.076±0.04 0.456±0.00
ENSMUST00000169534 0.072±0.00 N/A 0.031±0.00 0.020±0.01 N/A N/A N/A N/A N/A 0.111±0.00 0.035±0.00 0.313±0.16 0.081±0.08 0.376±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RD CIL_0008RD_0002 VISTA 5:72193972-72795406
CIL_0001MY CIL_0001MY_0002 CGP 5:72695978-72868483

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0001816 IMP cytokine production
GO:0001865 IGI NK T cell differentiation
GO:0002250 IMP adaptive immune response
GO:0003677 IEA DNA binding
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007202 IMP activation of phospholipase C activity
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032609 IGI interferon-gamma production
GO:0032633 IGI interleukin-4 production
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0046777 IEA protein autophosphorylation
GO:0050852 IMP T cell receptor signaling pathway
GO:0060335 IEA positive regulation of interferon-gamma-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015068 TXK TXK tyrosine kinase protein_coding Danio_rerio
ENSG00000074966 TXK TXK tyrosine kinase protein_coding Homo_sapiens

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