C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TXK tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000074966 TXK 9606 - 4:48066393-48134256 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264316 TXK-001 48066393-48134256 protein_coding
  ENST00000506073 TXK-015 48110569-48114545 protein_coding
  ENST00000507351 TXK-002 48067161-48080177 protein_coding
  ENST00000509681 TXK-006 48067388-48080178 nonsense_mediated_decay
  ENST00000510457 TXK-010 48089385-48134229 processed_transcript
  ENST00000514937 TXK-003 48066677-48080066 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264316ENST00000506073ENST00000507351ENST00000509681ENST00000510457ENST00000514937
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264316 0.401±0.00 N/A 0.013±0.00 N/A N/A N/A 0.412±0.00 0.095±0.01 0.284±0.00 N/A N/A 0.236±0.00 0.304±0.00
ENST00000506073 N/A N/A N/A N/A N/A 0.133±0.00 N/A N/A 2.773±0.00 N/A 0.180±0.03 0.540±0.00 N/A
ENST00000507351 N/A N/A 0.017±0.00 0.025±0.00 0.106±0.00 N/A N/A N/A N/A N/A 0.115±0.08 N/A N/A
ENST00000509681 N/A N/A N/A 0.034±0.00 1.245±0.00 N/A N/A 0.648±0.00 1.349±0.00 N/A N/A N/A N/A
ENST00000510457 N/A 0.104±0.00 0.079±0.06 0.071±0.00 0.484±0.41 N/A 0.515±0.00 0.129±0.00 0.997±0.00 0.011±0.00 0.152±0.08 N/A N/A
ENST00000514937 N/A 0.262±0.00 N/A 0.069±0.00 N/A N/A N/A N/A N/A N/A 0.068±0.00 0.106±0.00 0.270±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RD CIL_0008RD_0001 VISTA 4:47524449-48126035
CIL_0001MY CIL_0001MY_0001 CGP 4:48066393-48269864

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001012 IDA RNA polymerase II regulatory region DNA binding
GO:0001816 ISS cytokine production
GO:0001865 IEA NK T cell differentiation
GO:0002250 ISS adaptive immune response
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006468 IEA:TAS protein phosphorylation
GO:0007202 ISS activation of phospholipase C activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032609 IEA interferon-gamma production
GO:0032633 IEA interleukin-4 production
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0046777 IDA protein autophosphorylation
GO:0050852 ISS T cell receptor signaling pathway
GO:0060335 IDA positive regulation of interferon-gamma-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015068 TXK TXK tyrosine kinase protein_coding Danio_rerio
ENSMUSG00000054892 Txk TXK tyrosine kinase protein_coding Mus_musculus

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