C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2, group IVA (cytosolic, calcium-dependent)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000056220 Pla2g4a 10090 - 1:149829618-149961290 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070200 Pla2g4a-001 149829618-149961290 protein_coding
  ENSMUST00000111926 Pla2g4a-002 149829636-149922439 protein_coding
  ENSMUST00000134676 Pla2g4a-005 149932575-149961255 processed_transcript
  ENSMUST00000142040 Pla2g4a-003 149918877-149961284 retained_intron
  ENSMUST00000155438 Pla2g4a-004 149886184-149902199 processed_transcript
  ENSMUST00000190507 Pla2g4a-006 149886144-149961258 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070200ENSMUST00000111926ENSMUST00000190507
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070200 5.062±3.76 0.312±0.10 20.871±5.78 0.512±0.19 1.764±0.41 4.051±1.01 0.798±0.14 1.881±0.24 1.753±1.70 2.375±0.19 0.175±0.04 3.689±3.36 2.994±1.65 0.567±0.19
ENSMUST00000111926 N/A N/A N/A 0.210±0.14 N/A 1.795±0.47 0.092±0.00 N/A 0.066±0.00 0.327±0.00 0.126±0.03 N/A N/A N/A
ENSMUST00000190507 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.788±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004620 IEA phospholipase activity
GO:0004622 IEA lysophospholipase activity
GO:0004623 ISS phospholipase A2 activity
GO:0005509 ISS calcium ion binding
GO:0005544 ISS calcium-dependent phospholipid binding
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005829 IDA cytosol
GO:0009395 IEA phospholipid catabolic process
GO:0031410 IEA cytoplasmic vesicle
GO:0042127 IGI regulation of cell proliferation
GO:0046456 IMP icosanoid biosynthetic process
GO:0047498 IEA calcium-dependent phospholipase A2 activity
GO:0050482 IDA arachidonic acid secretion
GO:0071236 IDA cellular response to antibiotic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017141 pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) protein_coding Danio_rerio
ENSDARG00000024546 cpla2 cytosolic phospholipase a2 protein_coding Danio_rerio
ENSG00000116711 PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) protein_coding Homo_sapiens

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