C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leptin receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057722 Lepr 10090 + 4:101717404-101815352 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037552 Lepr-001 101717404-101815352 protein_coding
  ENSMUST00000102777 Lepr-002 101717404-101792258 protein_coding
  ENSMUST00000106921 Lepr-004 101717404-101813667 protein_coding
  ENSMUST00000128948 Lepr-007 101768047-101779593 processed_transcript
  ENSMUST00000145024 Lepr-005 101717407-101733317 protein_coding
  ENSMUST00000151733 Lepr-008 101788914-101792156 processed_transcript
  ENSMUST00000156402 Lepr-006 101771368-101782895 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037552ENSMUST00000102777ENSMUST00000106921ENSMUST00000128948ENSMUST00000156402
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037552 N/A N/A N/A 0.195±0.00 0.278±0.00 0.234±0.00 N/A 0.284±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000102777 0.939±0.00 0.272±0.08 N/A N/A 0.275±0.00 0.825±0.00 N/A N/A N/A N/A 0.148±0.06 1.312±0.00 158.416±201.78 0.019±0.00
ENSMUST00000106921 2.452±1.44 0.463±0.21 6.899±0.64 0.685±0.00 1.356±0.11 0.995±0.28 0.408±0.05 1.755±0.42 0.514±0.50 8.928±1.34 0.260±0.11 2.549±1.12 8.799±8.56 0.055±0.02
ENSMUST00000128948 N/A N/A N/A 1.680±0.00 N/A N/A N/A N/A 0.201±0.10 N/A N/A 5.790±0.00 349.204±329.59 0.109±0.00
ENSMUST00000156402 N/A 1.344±0.35 N/A N/A 1.322±0.00 N/A N/A N/A 0.159±0.00 N/A N/A N/A 431.536±100.93 0.067±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000264 CIL_000264_0002 CGP 4:101647718-101815352

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004888 TAS transmembrane signaling receptor activity
GO:0004896 IEA cytokine receptor activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0008203 IGI cholesterol metabolic process
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019222 TAS regulation of metabolic process
GO:0042802 IEA identical protein binding
GO:0043235 ISO receptor complex
GO:0045721 IMP negative regulation of gluconeogenesis
GO:0051346 IGI negative regulation of hydrolase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070961 lepr leptin receptor protein_coding Danio_rerio
ENSG00000116678 LEPR leptin receptor protein_coding Homo_sapiens

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