C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000060183 Cxcl11 10090 - 5:92359544-92365485 polymorphic_pseudogene
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077820 Cxcl11-201 92359547-92363277 protein_coding
  ENSMUST00000122808 Cxcl11-001 92359544-92365485 polymorphic_pseudogene

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077820ENSMUST00000122808
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077820 N/A N/A 0.036±0.01 0.017±0.01 0.161±0.04 0.140±0.11 0.045±0.00 0.051±0.04 0.204±0.24 0.060±0.00 0.103±0.06 0.043±0.04 0.037±0.03 0.011±0.00
ENSMUST00000122808 0.090±0.06 0.033±0.00 0.014±0.01 N/A 0.125±0.06 0.045±0.02 0.016±0.00 0.033±0.02 0.170±0.13 N/A 0.100±0.04 0.019±0.02 0.010±0.00 0.031±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00071M CIL_00071M_0002 CGP 5:92321331-92414628
CIL_0008VL CIL_0008VL_0002 VISTA 5:92327753-92928377
CIL_00071H CIL_00071H_0002 CGP 5:92331827-92414628

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0006935 ISS chemotaxis
GO:0006954 IEA inflammatory response
GO:0008009 TAS:ISS chemokine activity
GO:0008201 IEA heparin binding
GO:0010818 IEA T cell chemotaxis
GO:0030816 ISS positive regulation of cAMP metabolic process
GO:0042127 ISS regulation of cell proliferation
GO:0043950 ISS positive regulation of cAMP-mediated signaling
GO:0048248 ISS CXCR3 chemokine receptor binding
GO:0051281 ISS positive regulation of release of sequestered calcium ion into cytosol
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000169248 CXCL11 chemokine (C-X-C motif) ligand 11 protein_coding Homo_sapiens

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