C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinase suppressor of ras 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000061578 Ksr2 10090 + 5:117414000-117775003 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073347 Ksr2-002 117414000-117555942 retained_intron
  ENSMUST00000180430 Ksr2-001 117414000-117775003 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073347ENSMUST00000180430
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073347 0.017±0.01 0.146±0.00 N/A N/A N/A 0.048±0.02 0.018±0.00 N/A 0.022±0.01 0.018±0.00 N/A 0.120±0.04 0.016±0.00 N/A
ENSMUST00000180430 0.013±0.01 0.326±0.08 0.652±0.00 2.190±1.25 0.072±0.04 0.033±0.01 0.004±0.00 0.230±0.05 0.024±0.01 0.014±0.00 0.013±0.01 0.090±0.03 0.031±0.02 0.259±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005078 IDA MAP-kinase scaffold activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0019722 IGI calcium-mediated signaling
GO:0031434 IDA mitogen-activated protein kinase kinase binding
GO:0043410 IDA positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094526 ksr2 kinase suppressor of ras 2 protein_coding Danio_rerio
ENSG00000171435 KSR2 kinase suppressor of ras 2 protein_coding Homo_sapiens

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