C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinase suppressor of ras 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171435 KSR2 9606 - 12:117453012-117968983 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339824 KSR2-001 117453054-117968983 protein_coding
  ENST00000425217 KSR2-201 117453012-117968223 protein_coding
  ENST00000543793 KSR2-003 117539472-117555229 retained_intron
  ENST00000545002 KSR2-002 117517706-117677251 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000339824ENST00000425217
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000339824 N/A 0.247±0.00 1.204±0.54 0.029±0.01 0.094±0.00 N/A 0.105±0.00 N/A N/A 0.028±0.01 0.023±0.00 0.229±0.09
ENST00000425217 0.003±0.00 N/A 0.313±0.00 N/A N/A 0.005±0.00 0.003±0.00 0.015±0.00 0.002±0.00 0.006±0.00 0.005±0.00 0.130±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QM CIL_0001QM_0002 CGP 12:117208142-117968983

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005078 IEA MAP-kinase scaffold activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019722 IEA calcium-mediated signaling
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0043410 IEA positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094526 ksr2 kinase suppressor of ras 2 protein_coding Danio_rerio
ENSMUSG00000061578 Ksr2 kinase suppressor of ras 2 protein_coding Mus_musculus

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