C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hematopoietic SH2 domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062007 Hsh2d 10090 + 8:72189668-72200995 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072097 Hsh2d-201 72189668-72200958 protein_coding
  ENSMUST00000165324 Hsh2d-202 72193443-72200995 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072097ENSMUST00000165324
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072097 0.380±0.25 N/A 0.073±0.03 N/A 3.686±1.74 2.417±0.43 0.145±0.13 0.399±0.32 0.195±0.22 0.895±0.29 0.152±0.00 0.452±0.27 0.354±0.16 0.084±0.04
ENSMUST00000165324 0.267±0.09 0.096±0.05 0.081±0.00 0.063±0.04 0.950±0.05 N/A 0.094±0.08 0.105±0.00 0.093±0.07 0.163±0.03 N/A 0.218±0.21 0.439±0.30 0.169±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000IL CIL_0000IL_0002 CGP 8:72161200-72200995
CIL_00075Q CIL_00075Q_0002 CGP 8:72189668-72212837

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002903 IDA negative regulation of B cell apoptotic process
GO:0005070 IDA SH3/SH2 adaptor activity
GO:0005515 IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0009967 IDA positive regulation of signal transduction
GO:0042110 IDA T cell activation
GO:0051902 IDA negative regulation of mitochondrial depolarization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042908 hsh2d hematopoietic SH2 domain containing protein_coding Danio_rerio
ENSG00000196684 HSH2D hematopoietic SH2 domain containing protein_coding Homo_sapiens

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