C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC42 effector protein (Rho GTPase binding) 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063838 Cdc42ep5 10090 - 7:4151260-4164860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076831 Cdc42ep5-001 4151260-4164860 protein_coding
  ENSMUST00000140410 Cdc42ep5-003 4151776-4164442 protein_coding
  ENSMUST00000143825 Cdc42ep5-002 4151551-4164539 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076831ENSMUST00000143825
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076831 17.033±3.13 49.935±15.44 43.430±1.80 2.073±0.91 21.157±11.97 222.768±20.98 3.128±0.49 9.390±1.66 3.973±2.68 17.910±2.44 0.750±0.26 57.737±24.38 6.158±3.35 6.604±2.10
ENSMUST00000143825 N/A N/A N/A N/A N/A N/A N/A N/A 1.256±0.00 N/A 0.766±0.00 8.013±0.00 1.782±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005CN CIL_0005CN_0002 CGP 7:4147915-4164860

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0007254 IDA JNK cascade
GO:0007266 IDA Rho protein signal transduction
GO:0008360 IEA regulation of cell shape
GO:0016020 IEA membrane
GO:0017049 IEA GTP-Rho binding
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0031274 IEA positive regulation of pseudopodium assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062390 cdc42ep1b CDC42 effector protein (Rho GTPase binding) 1b protein_coding Danio_rerio
ENSG00000167617 CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 protein_coding Homo_sapiens

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